# Notebook from kjanjua26/Octofying-COVID19-Literature
Path: code/data_explainability/Data_Explainability_Visualizations.ipynb

# Data Explainability and Visualization
In this notebook, we perform exploratory data analysis on the published literature on COVID-19 and try to answer some basic questions such as

1. What is known about transmission, incubation, and environmental stability?
2. What do we know about COVID-19 risk factors?
3. Best medical care?
4. How the COVID-19 spreads and evolves?
5. What are some of the most promising vaccines available (if at all)?

Answering these questions will help clear doubts and answer basic questions with ease.

### Resources
1. https://towardsdatascience.com/topic-modelling-in-python-with-nltk-and-gensim-4ef03213cd21
2. https://www.youtube.com/watch?v=S6GVXk6kbcs_____no_output_____

<code>
# handling imports
import pandas as pd
import numpy as np
import matplotlib.pyplot as plt
from matplotlib import style
import tqdm, os, re, glob, json
from IPython.display import display
import nltk
nltk.download('wordnet')
from nltk.corpus import wordnet as wn
from nltk.stem.wordnet import WordNetLemmatizer
import random
from gensim import corpora
import pickle
import gensim
import collections
import pyLDAvis.gensim
from nltk.tokenize import word_tokenize
nltk.download('stopwords')
en_stop = set(nltk.corpus.stopwords.words('english'))
style.use('ggplot')
%matplotlib inline[nltk_data] Downloading package wordnet to /Users/Janjua/nltk_data...
[nltk_data]   Package wordnet is already up-to-date!
[nltk_data] Downloading package stopwords to
[nltk_data]     /Users/Janjua/nltk_data...
[nltk_data]   Package stopwords is already up-to-date!
basepath = "/Users/Janjua/Desktop/Projects/Octofying-COVID19-Literature/dataset"
datapath = "CORD-19-research-challenge"_____no_output_____papers = [x for x in glob.glob(os.path.join(basepath, datapath) + "/*/*/*.json")]
print('Total papers found: ', len(papers))
print(papers[:1])Total papers found:  33375
['/Users/Janjua/Desktop/Projects/Octofying-COVID19-Literature/dataset/CORD-19-research-challenge/custom_license/custom_license/86a998617c077f4fe2ab26214995a3548fbc0fc5.json']
for paper in papers:
    read_paper = json.load(open(paper))
    title = read_paper['metadata']['title']
    try:
        abstract = read_paper['abstract'][0]['text']
    except:
        abstract = "No abstract found"
    paper_text = ""
    for text in read_paper['body_text']:
        paper_text += text['text'] + '\n\n'
    print("="*100)
    print('Title: ', title)
    print("="*100)
    print('Abstract: ', abstract)
    print("="*100)
    print('Paper Contents: ', paper_text)
    print("="*100)
    break====================================================================================================
Title:  Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome
====================================================================================================
Abstract:  The recent emergence of the Middle East respiratory syndrome (MERS)-CoV, a close relative of the Severe Acute respiratory syndrome (SARS)-CoV, both of which caused a lethal respiratory infection in humans, reinforces the need for further understanding of coronavirus pathogenesis and the host immune response. These viruses have evolved diverse strategies to evade and block host immune responses, facilitating infection and transmission. Pathogenesis following infection with these viruses is characterized by a marked delay in the induction of Type I interferon (IFN I) and, subsequently, by a poor adaptive immune response. Therapies that expedite IFN I induction as well as interventions that antagonize immunoevasive virus proteins are thus promising candidates for immune modulation.
====================================================================================================
Paper Contents:  While most CoVs cause the common cold in humans, infection with two recently emerged CoVs, SARS-CoV and MERS-CoV, resulted in more severe pulmonary disease with alarmingly high case fatality rates [1] . SARS-CoV first emerged in Guangdong province of China in the winter of 2002 [2] . With a high rate of nosocomial transmission to healthcare professionals combined with a lack of precedence for a CoV outbreak, SARS-CoV spread across 29 countries infecting more than 8000 humans and resulting in a staggering 774 deaths (~10%) [3] . MERS-CoV was first reported in Saudi Arabia a decade later in June 2012 [4] . Cases were also detected in other parts of the Middle East including Jordan, Qatar, Oman and the United Arab Emirates. Virus was spread by travellers from the Arabian peninsula to Europe, Africa and other regions of Asia including, most recently, the Republic of Korea, infecting a total of 1626 people, with a case fatality rate of 36.0%, as of January 11, 2015 [5] [6] [7] [8] . Both of these outbreaks were notably characterized by an age-dependent increase in morbidity and mortality. Thus, during the SARS epidemic no patients under the age of 24 years died, while mortality was more than 50% in those over 65 years of age [9] .

Similarly, MERS also has a similar age-dependent pattern with elderly patients showing signs of more severe disease. MERS tends to be most severe in patients with co-morbidities such as diabetes, chronic pulmonary disease and renal disease [10] . While no more SARS cases were reported since 2004, new MERS cases continue to appear. The respiratory route of transmission of MERS-CoV combined with the geographical location of its persistence makes MERS a serious public health threat that if not curtailed, has the potential to develop as a major epidemic in the years to come. Although no MERS cases have been associated with the Hajj and Umrah pilgrimages, such large gatherings make this a potentially major problem [1] . In spite of the efforts by researchers across the globe, no effective drug treatments or vaccines have been formulated to control SARS or MERS. In this review we summarize the similarities and differences between SARS and MERS-CoV with an emphasis on the key features of the host immune response and tactics used by the viruses to evade the immune response.

Coronaviruses are enveloped RNA viruses that fall under the Nidovirus superfamily ( Figures  1, 2) . With a positive-sense single-stranded RNA genome of 31 kb, coronaviruses contain the largest RNA genome identified to date [11] . Both SARS and MERS-CoVs are betacoronaviruses, belonging to lineages b and c respectively. They share similar genomic structures with multiple open reading frames (ORFs). While the genes required for viral RNA replication are located on the 5'-terminal two thirds of the genome, those that encode the structural proteins are located on the 3' end [11] . Other genes, which encode accessory proteins not required for virus replication and viability, are distributed throughout the structural genes. MERS-CoV has five different accessory proteins while SARS-CoV has eight of them ( Figure 1 ) [12] . Some of these genes including some of the non-structural proteins encoded at the 5' end of the genome are involved in induction and modulation of innate immune responses in the host (humans).

The initiation of infection by CoVs begins with entry into host cells. Being close relatives in the phylogenetic tree, it may not be surprising that both SARS-CoV and MERS-CoV utilize large ectopeptidases on the surface of the host cell to gain entry; SARS-CoV binds to angiotensin converting enzyme 2 (ACE-2) and MERS-CoV attaches to dipeptidyl peptidase 4 (DPP4) [13, 14] . While it has been shown that the spike (S) glycoprotein of SARS-CoV underwent extensive mutation in the region that binds to ACE2 [15] , facilitating species to species transmission, the glycoprotein of MERS-CoV has not undergone substantial change in the DPP4-binding region during passage in humans [16, 17] . The absence of any mutation in DPP4-binding region suggests that receptor binding is not the rate-limiting step in virus transmission and human adaptation. After binding to their respective receptors, proteolytic cleavage of the S protein results in virus-cell fusion and release of genomic RNA into the cytosol of the host cell. Following the release of RNA, the virus undergoes transcription and replication on rearranged host membranes, including double-membrane vesicles (DMVs) [18] . Newly synthesized RNA is encapsidated within the nucleocapsid protein and then buds into vesicles derived from the endoplasmic reticulum-golgi intermediate compartment (ERGIC) for further assembly into new virions. These vesicles are eventually transported to the cell surface to be released outside the cell. Vijay Seroprevalence studies strongly support the notion that camels are one, if not the only, reservoir of MERS-CoV [17, [19] [20] [21] [22] [23] . Transmission from camels to humans is likely, although not all MERS patients have a history of direct camel exposure [24] . This could mean that other means of indirect transmission like consumption of camel milk or meat or transfer from an intermediate host to humans contribute to spread [20] .

All successful viruses have devised strategies to evade immune recognition by the host. These include mechanisms that are both active and passive. Common strategies are to delay the induction of the IFN response, block IFN signaling or counter the action of downstream effector molecules. Coronavirus RNA is not recognized in several cell types, partly because double stranded RNA, which is a potent inducer of IFN is shielded from recognition by intracellular helical sensors, such as RIG-I and MDA5, by containment in membranous structures, such as double membrane vesicles (DMVs) during replication [25, 26] . Also viral proteins nsp1, nsp3, nsp16, N protein, SARS-CoV ORF6 and ORF3b and MERS-CoV 4a and 4b inhibit IFN induction or signaling ( Figure 3 ). Nsp1 inhibits IFN signaling in SARS-CoV infected cells by inhibiting phosphorylation of STAT1 as well as by promoting host gene mRNA degradation [12] . Nsp1 also inhibits host gene expression by binding to the 40S ribosomal subunit and by inactivating the translation activity of the ribosomes. Nsp3 through its papain-like protease (PLP) domain inhibits IFN I production by deubiquitinating IRF3 and prevents its nuclear translocation [27] . PLP physically interacts with TRAF3, TBK1, IKKε, STING and IRF3, and inhibits phosphorylation and dimerization of IRF3 inhibiting IFN expression [28] . Nsp16, by effecting 2'-O methylation, renders viral RNA indistinguishable from host cell RNA [29, 30] . N protein inhibits activator protein 1 (AP1) signaling and protein kinase R (PKR) function as well as nuclear factor-κB (NFκB) activation [12] . The ORF6 protein inhibits IFN signaling by binding to karyopherin-α2, which prevents nuclear translocation of proteins containing classical nuclear import signals, including STAT1, crucial for IFN signaling [31] . MERS-CoV accessory protein ORF4a antagonizes IFN induction through MDA5 by sequestrating viral dsRNA and preventing it from binding to MDA5 [32] [33] [34] . MERS-CoV also encodes accessory protein ORF4b, which has been shown to localize to the nucleus and inhibit IFN I synthesis and NFκB signaling pathways [27] .

Further insights into the immune response against MERS-CoV are hindered by the absence of a good animal model that recapitulates the human disease. Mouse DPP4 does not support MERS-CoV replication but mice are susceptible if hDPP4 is supplied exogenously using a replication deficient adeno-virus expressing hDPP4 (Ad5-hDPP4) or if mice are transgenic or "knocked-in" for hDPP4 [35] [36] [37] . Use of Ad5-hDPP4 transduction allows genetically deficient mice to be infected without additional crossing. MERS-CoV infection of transduced Ad5-hDPP4 demonstrated the need for IFN I induction for protection and showed that virus-specific T cells were required for MERS-CoV clearance. Rabbits, macaques and marmosets can also be infected with MERS-CoV although these animals develop few signs of clinical disease (rabbits, macaques) or are difficult to obtain (marmosets) [38] [39] [40] [41] . Rabbits and macaques may be useful for study of mild human disease but not for understanding pathogenesis in severely ill patients. The anti-virus T cell response is critical for virus clearance. The T cell response is initiated by the uptake of viral antigen (Ag) by respiratory dendritic cells (rDC) and rDC migration to draining lymph nodes (DLN), where they prime naïve virus specific T cells. Following priming, naïve T cell undergo activation and clonal proliferation, which then migrate from the DLN to the site of infection (lungs). At this site, they secrete various anti-viral chemokines, cytokines and cytotoxic molecules that can directly or indirectly inhibit viral replication. Severely ill MERS and SARS patients exhibited severe leukopenia with marked lymphopenia, impaired activation of T cells and poor anti-virus antibody responses contributing to delayed kinetics of virus clearance [9, 42] . In addition, an effective T cell response is required to shut off the initial cytokine response. Thus, severe SARS was also characterized by prolonged cytokine and interferon expression, contributing to a "cytokine storm" in these patients. Studies of virus-specific CD4 and CD8 T cells in patients recovered from SARS identified several immunogenic epitopes localized to the spike (S) and nucleocapsid (N) proteins [43] . However no information is available yet regarding the T cell epitopes recognized in MERS-CoV-infected patients.

As in many viral infections, development of neutralizing antibodies is required to prevent infection after secondary exposure to the pathogen. The anti-SARS-CoV antibody response appeared to be transient, with antibodies not detected 6 years after infection. In contrast, T cell responses were still detectable. [44] . The transient nature of the antibody response raises concerns that SARS recovered patients, if reinfected, would not be protected from severe disease. Of note, none of these studies examined the mucosal antibody response, which may be very important for protection.

Mouse and macaque models of SARS infection have provided a wealth of knowledge regarding the immune response against CoV in general and SARS-CoV in particular. Human strains of SARS-CoV infect macaques and mice but generally do not cause significant clinical disease [45] . However, upon mouse adaptation, the virus causes severe disease, characterized by a lethal respiratory infection [46] . In some strains, young (6-10 week) mice are completely resistant to disease, remaining without signs of disease even in the absence of Type 1 interferon signaling, while others are highly sensitive [31] . Aged mice of all strains are susceptible to disease, mimicking the age-dependent susceptibility observed in humans. SARS-CoV-infected mice have been useful for identifying host genes important in pathogenesis. Studies with mouse adapted SARS-CoV showed that more severe disease was characterized by inefficient immune activation, such as reduced expression of MHCII, CD86, accompanied by poor CD4 and CD8 T cell responses. Reversing inefficient activation of innate immune cells in mice using TLR ligands such as poly I-C or by depleting inhibitory alveolar macrophages using clodronate liposomes rescued mice from lethal disease [47] . These interventions resulted in enhanced migration of dendritic cells to draining lymph nodes and consequent development of a protective T cell response and enhanced kinetics of virus clearance. Experiments with macaques also showed that aged macaques developed a robust, but dysregulated host innate response against SARS-CoV compared to young animals and this correlated with worse outcomes after infection [48] .

Another study showed that age-dependent increases in the levels of a prostaglandin, PGD 2 , in the lungs of aged mice inhibited rDC migration to DLN, which in turn impeded virus- specific T cell responses, rendering aged mice susceptible to severe SARS-CoV infection [49] . Blockade of PGD 2 signaling through its receptor, DP1, resulted in enhanced rDC migration to DLN and virus-specific T cell responses. Given the propensity of MERS-CoV to cause severe disease in aged individuals, it is likely that PGD 2 has a similar role in the context of MERS-CoV infections.

Delayed immune activation was also observed in SARS-CoV-infected human macrophages and dendritic cells, suggesting that the virus is able to evade the immune response. Further SARS-CoV only abortively infects DCs and macrophages [9] . In contrast, MERS-CoV productively infects human macrophages [50] . Notably, MERS-CoV additionally infects activated T cells, which may contribute to disease severity [51] . Similar effects occur in infected airway epithelial cells, the first target cell for SARS-CoV and MERS-CoV replication. One study compared infection of human epithelial Calu-3 2B4 cells with MERS-CoV and SARS-CoV, highlighting and contrasting the potential antiviral mechanisms mounted by the host against the two viruses. Infection of these cells induced activation of several RNA sensors at approximately the same time post infection. However the IFN response was slightly delayed in cells infected with SARS-CoV compared to MERS-CoV. Additionally, a notable difference was the specific down regulation of the antigen presentation pathway after MERS-CoV infection, which was upregulated after SARS-CoV infection [52] . Thus, although these two viruses are closely related to one another and both elicit delayed immune responses, they induce a significantly different host transcriptional response, suggesting that 'MERS is not SARS'.

The ease with which SARS-CoV and MERS-CoV, as well as other respiratory coronaviruses such as HCoV-OC43 [53, 54, 16] crossed species to infect humans make it all the more likely that serious CoV outbreaks will continue to emerge. Fittingly, exactly a decade after SARS, MERS emerged with an even higher mortality rate. Three years after the emergence of MERS, the lack of detailed information about the human disease and of a broadly useful animal model has hindered progress in understanding MERS-CoV disease and immune responses. The recent outbreak in South Korea with over 180 cases emphasizes the importance of instituting proper infection control measures, especially in hospital settings and in developing vaccines and drugs to counter the virus.

• MERS-CoV is a newly emerging betacoronavirus causing lethal human respiratory infection.

• MERS-CoV is transmitted from camels in the Arabian peninsula.

• Susceptibility to MERS-CoV infection is greatest in individuals with underlying morbidities.

• No vaccines or anti-viral therapies are available for prophylaxis or treatment.

• MERS-CoV and SARS-CoV have evolved effective immune evasion strategies. Signaling of MAVS results in activation of various kinases, which phosphorylate IRF3, resulting in its dimerization and trafficking to the nucleus for inducing IFN I production. IFN I thus produced will signal through IFNα/β receptor resulting in its phosphorylation by JAK1 and TYK1. This will result in STAT1/STAT2 complex formation, activation and localization into the nucleus using import factors such as karyopherin α1 (Kα1) and karyopherin α2 (Kα2), which will activate various interferon stimulated response elements (ISREs) to bring about an antiviral state. As depicted in the schematic, CoVs have developed strategies to evade/inhibit host innate immune functions, some of which are specific to SARS-CoV [26] (blue) and MERS-CoV (magenta) and some which are shared between the two viruses (red). Nsp1 inhibits phosphorylation of STAT1, promotes host gene mRNA degradation, and also inhibits host mRNA translation. Nsp3 interacts with IRF3, inhibiting its phosphorylation, dimerization and nuclear translocation. Nsp16 renders the virus unrecognizable by cellular sensors MDA5 and RIG-I. N protein inhibits AP1 and NFκB signaling and PKR function.

====================================================================================================
def draw_horizontal_lines(times):
    print("="*times)

def read_papers():
    papers_contents = []
    for paper in tqdm.tqdm(papers):
        read_paper = json.load(open(paper))
        title = read_paper['metadata']['title']
        try:
            abstract = read_paper['abstract'][0]['text']
        except:
            abstract = "No abstract found"
        paper_text = ""
        for text in read_paper['body_text']:
            paper_text += text['text'] + '\n\n'
        papers_contents.append([title, abstract, paper_text])
    return papers_contents_____no_output_____print("Reading Papers!")
draw_horizontal_lines(100)
papers = read_papers()
print(papers[0])
draw_horizontal_lines(100)  0%|          | 58/33375 [00:00<00:58, 571.19it/s]draw_horizontal_lines(100)
print("Create a dataframe for processing!")
draw_horizontal_lines(100)
df_covid = pd.DataFrame(papers, columns=["title", "abstract", "text"])
display(df_covid.head())====================================================================================================
Create a dataframe for processing!
====================================================================================================
def keyword_based_search(keyword, df):
    result = df[df['text'].str.contains(keyword)]
    text_content = result.text.values
    title = result.title.values
    display(result.head())
    relevant_sentences = {'title': [], 'sents': []}
    for sent in tqdm.tqdm(range(len(text_content))):
        sentences = text_content[sent].split('.')
        relevant_sentences['title'].append(title[sent])
        relevant_sentences['sents'].append([s for s in sentences if keyword in s])
    return relevant_sentences

draw_horizontal_lines(100)
print("Getting the subset of DF containing the keyword!")
draw_horizontal_lines(100)
relevant_sentences = keyword_based_search("pregnant women", df_covid)
for i in range(5):
    draw_horizontal_lines(100)
    print("Title: ", relevant_sentences['title'][i])
    print("Sentences: ", relevant_sentences['sents'][i])
    print()====================================================================================================
Getting the subset of DF containing the keyword!
====================================================================================================

</code>

## Topic Modelling - Latent Dirichlet allocation
In this section, we perform topic modelling on the corpus (research papers) to retrieve the papers with relevant information._____no_output_____

<code>
def get_tokens(text):
    return word_tokenize(text)

def get_lemma(word):
    lemma = wn.morphy(word)
    if lemma is None:
        return word
    else:
        return lemma

def get_lemma2(word):
    return WordNetLemmatizer().lemmatize(word)

def prepare_text_for_lda(text):
    tokens = get_tokens(text)
    tokens = [token for token in tokens if len(token) > 4]
    tokens = [token for token in tokens if token not in en_stop]
    tokens = [get_lemma(token) for token in tokens]
    return tokens

def generate_tokens_for_searched_sentences():
    text_data = []
    title_to_token = {'title': [], 'tokens':[]}
    for ix in range(len(relevant_sentences['title'])):
        full_text = ''.join(x for x in relevant_sentences['sents'][ix])
        title = relevant_sentences['title'][ix]
        tokens = prepare_text_for_lda(full_text)
        if random.random() > 0.7:
            title_to_token['title'].append(title)
            title_to_token['tokens'].append(tokens)
            text_data.append(tokens)
    return text_data, title_to_token

def get_corpus(token_data):
    dictionary = corpora.Dictionary(token_data)
    corpus = [dictionary.doc2bow(text) for text in token_data]
    pickle.dump(corpus, open('corpus.pkl', 'wb'))
    dictionary.save('dictionary.gensim')
    print("Saved dictionary!")
    return corpus, dictionary

tokens_data, title_to_token = generate_tokens_for_searched_sentences()
corpus, dictionary = get_corpus(tokens_data)Saved dictionary!
NUM_TOPICS = 10
ldamodel = gensim.models.ldamodel.LdaModel(corpus, num_topics = NUM_TOPICS, id2word=dictionary, passes=15)
ldamodel.save('model5.gensim')
topics = ldamodel.print_topics(num_words=10)
for topic in topics:
    print(topic)(0, '0.063*"woman" + 0.055*"pregnant" + 0.018*"vaccine" + 0.013*"include" + 0.012*"infection" + 0.008*"study" + 0.007*"pregnancy" + 0.006*"report" + 0.006*"individual" + 0.006*"infant"')
(1, '0.066*"woman" + 0.063*"pregnant" + 0.021*"infection" + 0.017*"disease" + 0.010*"child" + 0.007*"mortality" + 0.007*"chronic" + 0.006*"vaccination" + 0.006*"study" + 0.006*"include"')
(2, '0.061*"woman" + 0.054*"pregnant" + 0.010*"vaccine" + 0.010*"disease" + 0.008*"increase" + 0.008*"program" + 0.008*"child" + 0.008*"infant" + 0.008*"among" + 0.007*"pregnancy"')
(3, '0.061*"pregnant" + 0.061*"woman" + 0.012*"child" + 0.010*"COVID-19" + 0.009*"anaemia" + 0.009*"study" + 0.009*"infection" + 0.009*"fetus" + 0.008*"pregnancy" + 0.008*"cause"')
(4, '0.026*"woman" + 0.025*"pregnant" + 0.014*"vaccine" + 0.010*"provide" + 0.009*"health" + 0.007*"mother" + 0.007*"communication" + 0.007*"program" + 0.006*"immunization" + 0.005*"child"')
(5, '0.056*"woman" + 0.052*"pregnant" + 0.025*"infection" + 0.011*"vaccine" + 0.010*"study" + 0.008*"population" + 0.007*"clinical" + 0.007*"severe" + 0.007*"newborn" + 0.006*"control"')
(6, '0.038*"pregnant" + 0.038*"woman" + 0.028*"patient" + 0.025*"infection" + 0.013*"disease" + 0.010*"sample" + 0.010*"chronic" + 0.008*"treatment" + 0.008*"child" + 0.007*"transplant"')
(7, '0.071*"woman" + 0.059*"pregnant" + 0.024*"influenza" + 0.013*"infection" + 0.009*"among" + 0.009*"study" + 0.009*"response" + 0.008*"non-pregnant" + 0.008*"death" + 0.007*"pdm09"')
(8, '0.061*"pregnant" + 0.060*"woman" + 0.018*"child" + 0.014*"include" + 0.013*"person" + 0.012*"influenza" + 0.011*"group" + 0.010*"people" + 0.009*"vaccine" + 0.009*"medical"')
(9, '0.020*"woman" + 0.020*"pregnant" + 0.014*"person" + 0.008*"product" + 0.007*"vaccine" + 0.007*"control" + 0.005*"result" + 0.005*"virus" + 0.005*"group" + 0.005*"order"')
lda = gensim.models.ldamodel.LdaModel.load('model5.gensim')
lda_display = pyLDAvis.gensim.prepare(lda, corpus, dictionary, sort_topics=False)
pyLDAvis.display(lda_display)/usr/local/lib/python3.7/site-packages/pyLDAvis/_prepare.py:257: FutureWarning: Sorting because non-concatenation axis is not aligned. A future version
of pandas will change to not sort by default.

To accept the future behavior, pass 'sort=False'.

To retain the current behavior and silence the warning, pass 'sort=True'.

  return pd.concat([default_term_info] + list(topic_dfs))
draw_horizontal_lines(100)
print("The papers in this results are: ")
for ix, paper in enumerate(title_to_token['title']):
    if len(paper) > 0:
        print("Nbr: ", ix, " Title: ", paper)
draw_horizontal_lines(100)====================================================================================================
The papers in this results are:
Nbr:  0  Title:  Public Willingness to Take a Vaccine or Drug Under Emergency Use Authorization during the 2009 H1N1 Pandemic
Nbr:  1  Title:  Ribavirin inhibits Zika virus (ZIKV) replication in vitro and suppresses viremia in ZIKV-infected STAT1-deficient mice
Nbr:  2  Title:  Appendix 9-2 Building Emergency Management Plan Building Emergency Procedures Manual
Nbr:  3  Title:  Rates of respiratory virus-associated hospitalization in children aged <5 years in rural northern India
Nbr:  4  Title:  Antiviral Agents
Nbr:  5  Title:  The Sustained Value of an Early Pregnancy Assessment Clinic in the Management of Early Pregnancy Complications: A 10-Year Retrospective Study
Nbr:  6  Title:  Therapeutic Targets for the Treatment of Hepatitis E Virus Infection HHS Public Access
Nbr:  8  Title:  The Lancet Commissions The Tsinghua-Lancet Commission on Healthy Cities in China: unlocking the power of cities for a healthy China Executive summary
Nbr:  11  Title:  Liver and Bile Duct Infections
Nbr:  12  Title:  Lancet mass gatherings medicine 1 Hajj: infectious disease surveillance and control
Nbr:  13  Title:  Pneumonia in the tropics: Report from the Task Force on tropical diseases by the World Federation of Societies of Intensive and Critical Care Medicine
Nbr:  14  Title:  UK malaria treatment guidelines 2016
Nbr:  16  Title:  Tularaemia: A challenging zoonosis
Nbr:  17  Title:  Food Safety: Emerging Pathogens
Nbr:  18  Title:  Preclinical Toxicology of Vaccines 1
Nbr:  19  Title:  Coming of Age in Travel Medicine and Tropical Diseases: A Need for Continued Advocacy and Mentorship
Nbr:  20  Title:  Angiotensin converting enzyme 2: A new important player in the regulation of glycemia
Nbr:  21  Title:  Surveillance of upper respiratory infections using a new multiplex PCR assay compared to conventional methods during the influenza season in Taiwan
Nbr:  22  Title:  Environmental and Occupational Health Learning Objectives
Nbr:  23  Title:  Original Contributions Intrauterine Latent Herpes Simplex Virus Infection: I~ Spontaneous Abortion Received from the Departments of *Pathology and :~Obstet- rics, Green Hospital of Scripps Clinic, La Jolla, and the ?
Nbr:  24  Title:  Influenza A ☆
Nbr:  25  Title:  Emergency Caesarean delivery in a patient with confirmed coronavirus disease 2019 under spinal anaesthesia
Nbr:  26  Title:  Review Crimean-Congo haemorrhagic fever
Nbr:  27  Title:  The Lancet Commissions The legal determinants of health: harnessing the power of law for global health and sustainable development Executive summary
Nbr:  28  Title:  SECTION A Epidemiology and Control of Infectious Diseases PART I Understanding, Controlling, and Preventing Infectious Diseases
Nbr:  29  Title:  e World Health Organization Country Office, Afghanistan f World Health Organization Country Office, Lebanon g World Health Organization Country Office, Morocco h Senior Consultant & Medical Epidemiologist, Communicable Diseases Adviser to Health Affairs, Ministry of Health
Nbr:  32  Title:  Ethics
Nbr:  34  Title:  The Lancet Gastroenterology & Hepatology Commission Liver diseases in the Asia-Pacific region: a Lancet Gastroenterology & Hepatology Commission
Nbr:  36  Title:  7 Colds, Influenza and Performance SOCIO-ECONOMIC EFFECTS OF RESPIRATORY ILLNESSES
Nbr:  38  Title:  The impact of influenza and respiratory syncytial virus on hospitalizations for lower respiratory tract infections in young children: Slovenia, 2006-2011
Nbr:  39  Title:  Codelivery of improved immune complex and virus-like particle vaccines containing Zika virus envelope domain III synergistically enhances immunogenicity
Nbr:  40  Title:  Abstracts from the 11th International Congress of Behavioral Medicine PM MULTILEVEL ANALYSES OF REPEATED AND CLUSTERED OBSERVATIONS: THE GENERALISATION FROM SIMPLE LINEAR MODELS TO LINEAR MIXED MODELS AND VARIANCE COMPONENT MODELS
Nbr:  43  Title:  Revisitation of autoimmune hypophysitis: knowledge and uncertainties on pathophysiological and clinical aspects
Nbr:  45  Title:  Journal Pre-proof Why are pregnant women susceptible to viral infection: an immunological viewpoint? Why are pregnant women susceptible to viral infection: an immunological viewpoint?
Nbr:  46  Title:  Taking the bull by the horns: Ethical considerations in the design and implementation of an Ebola virus therapy trial
Nbr:  47  Title:  European Cystic Fibrosis Society Standards of Care: Framework for the Cystic Fibrosis Centre
Nbr:  48  Title:  Oral presentations New aspects of emerging Clostridium difficile infections (CDI) S2 Pros and cons of molecular fingerprinting for Clostridium difficile infections
Nbr:  51  Title:  Passive Monoclonal and Polyclonal Antibody Therapies
Nbr:  52  Title:  Health shocks and their long-lasting impact on health behaviors: Evidence from the 2009 H1N1 pandemic in Mexico
Nbr:  53  Title:  Comment
Nbr:  55  Title:  What is the Role of Respiratory Viruses in Community-Acquired Pneumonia? What is the Best Therapy for Influenza and Other Viral Causes of Community-Acquired Pneumonia?
Nbr:  56  Title:  Liver and Bile Duct Infections
Nbr:  57  Title:  Molecular Diagnostics and Comparative Genomics in Clinical Microbiology Chapter 30
Nbr:  59  Title:  MOLECULAR BIOLOGY OF RUBELLA VIRUS
Nbr:  61  Title:  Case Studies in Public Health
Nbr:  62  Title:  Cephalotaxine inhibits Zika infection by impeding viral replication and stability
Nbr:  63  Title:  New insights into the aryl hydrocarbon receptor as a modulator of host responses to infection
Nbr:  64  Title:  Viral Diseases
Nbr:  67  Title:  Biological Agents
Nbr:  68  Title:  Economic and Political Impact of Ebola Virus Disease
Nbr:  69  Title:  Quantitative risk assessment for food-and waterborne viruses
Nbr:  70  Title:  International Laws and Food-Borne Illness
Nbr:  71  Title:  A review on the antagonist Ebola: A prophylactic approach
Nbr:  75  Title:  REVIEW A Systematic Approach to Novel Virus Discovery in Emerging Infectious Disease Outbreaks
Nbr:  76  Title:  Air-borne/droplet infections Chapter 22 Occupational Infectious Diseases
Nbr:  77  Title:  Gastrointestinal System DIAGNOSTIC AND THERAPEUTIC PROCEDURES Nasogastric Tube Placement SECTION I Body and Organ Systems UPPER GI SECTION I Body and Organ Systems
Nbr:  78  Title:  Nosocomial or Hospital-acquired Infections: An Overview
Nbr:  79  Title:  The National Vaccine Advisory Committee at 30: Impact and opportunity
Nbr:  80  Title:  Maternal Infection and Adverse Fetal and Neonatal Outcomes
Nbr:  81  Title:  Rapid Review The psychological impact of quarantine and how to reduce it: rapid review of the evidence
Nbr:  82  Title:  Advax TM , a novel microcrystalline polysaccharide particle engineered from delta inulin, provides robust adjuvant potency together with tolerability and safety
Nbr:  84  Title:  Epidemiology of Viral Pneumonia
Nbr:  85  Title:  Review Emerging Pathogens: Challenges and Successes of Molecular Diagnostics
Nbr:  86  Title:  Oropharyngeal and Tonsillar Infections
Nbr:  87  Title:  Ecology of Increasing Diseases: Population Growth and Environmental Degradation
Nbr:  88  Title:  Haematological Diseases in the Tropics
Nbr:  89  Title:  Severe Childhood Respiratory Viral Infections
Nbr:  91  Title:  LYMPHOCYTOSIS, LYMPHOCYTOPENIA, HYPERGAMMAGLOBULINEMIA, AND HYPOGAMMAGLOBULINEMIA
Nbr:  92  Title:  Recent advances in pharmacological research on Ecklonia species: a review
Nbr:  93  Title:  Impact of Historic Migrations and Evolutionary Processes on Human Immunity
Nbr:  94  Title:  Health surveillance, biosafety and emergence and re-emergence of infectious diseases in Brazil
Nbr:  95  Title:  Journal Pre-proof Coronavirus Disease (COVID-19): A primer for emergency physicians Title: Coronavirus Disease (COVID-19): A Primer for Emergency Physicians
Nbr:  96  Title:  Grand Round Subacute sclerosing panencephalitis in pregnancy
Nbr:  97  Title:  8 Control of intestinal diseases by dietary supplementation with antibodies
Nbr:  98  Title:  Vaccine development for emerging virulent infectious diseases
Nbr:  99  Title:  PUBLICACIÓN OFICIAL DE LA SOCIEDAD ESPAÑOLA DE ENFERMEDADES INFECCIOSAS Y MICROBIOLOGÍA CLÍNICA
Nbr:  100  Title:  Molecular Microbiology
Nbr:  101  Title:  Two measles clusters in connection with short inner-European air travels indicating impediments to effective measles control: A cluster analysis
Nbr:  102  Title:  "Your Health Essential for Your Hajj": Muslim pilgrims' knowledge, attitudes and practices regarding Middle East respiratory syndrome coronavirus (MERS-CoV) during Hajj season
Nbr:  103  Title:  Influenza and Viral Pneumonia
Nbr:  104  Title:  Sheff ield)
Nbr:  105  Title:  Herbal plants and plant preparations as remedial approach for viral diseases
Nbr:  106  Title:  Middle East respiratory syndrome coronavirus (MERS-CoV): Prevention in travelers
Nbr:  107  Title:  Eff ect of the Ebola-virus-disease epidemic on malaria case management in Guinea, 2014: a cross-sectional survey of health facilities
Nbr:  108  Title:  HUMAN MILK*
Nbr:  109  Title:  8 Protection of Travelers
Nbr:  110  Title:  Novel drugs targeting Toll-like receptors for antiviral therapy
Nbr:  111  Title:  Application of transmission electron microscopy to the clinical study of viral and bacterial infections: Present and future
Nbr:  113  Title:  Paediatrics in the Tropics
Nbr:  114  Title:  Pharmacokinetic and Pharmacodynamic Considerations for Drugs Binding to Alpha-1-Acid Glycoprotein
Nbr:  115  Title:  Commentary What to Expect When You're Expecting Zika
Nbr:  116  Title:  The Cell Biology of Acute Childhood Respiratory Disease: Therapeutic Implications
Nbr:  117  Title:  Vomiting, Diarrhea, Constipation, and Gastroenteritis
Nbr:  118  Title:  Respiratory syncytial virus
Nbr:  119  Title:  Review Article · Übersichtsarbeit Pathogen Inactivation of Platelet and Plasma Blood Components for Transfusion Using the INTERCEPT Blood System™
Nbr:  120  Title:  Response to the 2009 pandemic: Effect on influenza control in wealthy and poor countries
Nbr:  121  Title:  Infection-control knowledge, attitude, practice, and risk perception of occupational exposure to Zika virus among nursing students in Korea: A cross-sectional survey ଝ,ଝଝ
Nbr:  122  Title:  Comment 760 www
Nbr:  123  Title:  Rapid response to an emerging infectious disease e Lessons learned from development of a synthetic DNA vaccine targeting Zika virus
Nbr:  124  Title:  Current research on respiratory viral infections: Third International Symposium
Nbr:  125  Title:  Routes of Transmission in the Food Chain
Nbr:  126  Title:  ScienceDirect
Nbr:  127  Title:  Acceptability of A/H1N1 vaccination during pandemic phase of influenza A/H1N1 in Hong Kong: population based cross sectional survey
Nbr:  128  Title:  33 BACTERIAL PNEUMONIA AND LUNG ABSCESS
Nbr:  129  Title:  Non-invasive bioluminescence imaging of HCoV-OC43 infection and therapy in the central nervous system of live mice
Nbr:  131  Title:  Early inhibitors of human cytomegalovirus: State-of-art and therapeutic perspectives
Nbr:  132  Title:  Microbial contamination of drinking water and disease outcomes in developing regions
Nbr:  133  Title:  Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: a nested case-control study of the Drakenstein Child Health Study
Nbr:  134  Title:  The immunosuppressed traveler: infection risks with autoimmunity and immunosuppression, vaccinations, and general travel advice
Nbr:  135  Title:  Organization of Public Health Systems Learning Objectives
Nbr:  137  Title:  An ethical framework for evaluation of public health plans: a systematic process for legitimate and fair decision-making
Nbr:  140  Title:  Respiratory Viral Infections in Transplant and Oncology Patients
Nbr:  141  Title:  Pandemic (H1N1) 2009 influenza
Nbr:  142  Title:  Acute Respiratory Infections in a Recently Arrived Traveler to Your Part of the World*
Nbr:  144  Title:  Perspectives in Foodbor ne Illness
Nbr:  145  Title:  Preemptive and Proactive Strategies for Food Control and Biosecurity
Nbr:  146  Title:  Repurposing an HIV Drug for Zika Virus Therapy
Nbr:  147  Title:  Hepatobiliary Disease
Nbr:  148  Title:  Pandemic Infl uenza Planning in the United States from a Health Disparities Perspective Search past Issues
Nbr:  149  Title:  Influenza and Endemic Viral Pneumonia
Nbr:  150  Title:  RACE, GENDER AND TOTAL KNEE REPLACEMENT CONSIDERATION: THE ROLE OF SOCIAL SUPPORT
Nbr:  151  Title:  Public health services in Shenzhen: a case study
Nbr:  152  Title:  Severe Measles Infection The Spectrum of Disease in 36 Critically Ill Adult Patients
Nbr:  153  Title:  Clinical Microbiology Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV)
Nbr:  154  Title:  Environmental Risk Factors for Stroke and Cardiovascular Disease
Nbr:  155  Title:  The effective reproduction number of pandemic influenza: Prospective estimation
Nbr:  156  Title:  Influenza A
Nbr:  157  Title:  Experimental Infections of the Common Marmoset (Callithrix jacchus)
Nbr:  158  Title:  Oral presentations Abstract ID: 4444 Outbreak of Panton-Valentine Leucocidin- associated Staphylococcus aureus (PVL-SA) skin infection linked to a diving club at a national sports centre: Case management, environmental assessment and control measures
Nbr:  159  Title:  R2250 H1N1 virus infection: review of chest radiographic findings
Nbr:  160  Title:  PATHOGENESIS Contents Airborne Infectious Microorganisms Aminoglycosides, Bioactive Bacterial Metabolites Antibiotic Resistance Antifungal Agents Antiviral Agents Bacteriophage Therapy: Past and Present Bacteriophage Therapy: Potential and Problems -Lactam Antibiotics Cyanobacterial Toxins Diagnostic Microbiology Emerging Infections Enteropathogenic Infections Epidemiological Concepts and Historical Examples Exotoxins Food and Waterborne Illnesses Fungal Infections, Cutaneous Fungal Infections, Systemic Fungicides and other Chemical Approaches for use in Plant Disease Control Gastrointestinal Microbiology in the Normal Host Global Burden of Infectious Diseases Glycopeptides, Antimicrobial Immune Suppression Immunity Infectious Waste Management Lipopolysaccharides (Endotoxins) Macrolides Mycotoxins Oral Microbiology Plant Disease Resistance: Natural, Non-Host Innate or Inducible Plant Disease Resistance: Breeding and Transgenic Approaches Plant Pathogens and Disease: General Introduction Plant Pathogens and Disease: Newly Emerging Diseases Plant Pathogens, Bacterial Plant Pathogens, Minor (Phytoplasmas) Prions Quinolones Sexually Transmitted Diseases Skin Microbiology Subversion of Host Defences by Microbes 175 Surveillance of Infectious Diseases Vaccine Development: The Development of Avian Influenza Vaccines for Human Use Vaccines, Viral Viral Pathogens of Domestic Animals and Their Impact on Biology, Medicine and Agriculture Zoonoses Airborne Infectious Microorganisms
Nbr:  161  Title:  Loop-mediated isothermal amplifi cation (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases
Nbr:  162  Title:  Therapeutic potentials of Houttuynia cordata Thunb. against inflammation and oxidative stress: A review
Nbr:  163  Title:  RNA interference inhibits hepatitis E virus mRNA accumulation and protein synthesis in vitro
Nbr:  165  Title:  Recent Advances in Hantavirus Molecular Biology and Disease
Nbr:  166  Title:  Benefits of using heterologous polyclonal antibodies and potential applications to new and undertreated infectious pathogens
Nbr:  168  Title:  PUBLICACIÓN OFICIAL DE LA SOCIEDAD ESPAÑOLA DE ENFERMEDADES INFECCIOSAS Y MICROBIOLOGÍA CLÍNICA
Nbr:  169  Title:  Adolescents and Pets
Nbr:  170  Title:  e World Health Organization Country Office, Afghanistan f World Health Organization Country Office, Lebanon g World Health Organization Country Office, Morocco h Senior Consultant & Medical Epidemiologist, Communicable Diseases Adviser to Health Affairs, Ministry of Health
Nbr:  171  Title:  PUBLICACIÓN OFICIAL DE LA SOCIEDAD ESPAÑOLA DE ENFERMEDADES INFECCIOSAS Y MICROBIOLOGÍA CLÍNICA
Nbr:  172  Title:  Reverse genetics approaches to combat pathogenic arenaviruses
Nbr:  173  Title:  Current concepts in the prevention of pathogen transmission via blood/plasma-derived products for bleeding disorders ☆-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Nbr:  174  Title:  Advances in the Renin Angiotensin System: Focus on Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7)
Nbr:  175  Title:  Table 9-2 n Diseases and Agents "to watch" in Terms of Zoonotic Potential
Nbr:  176  Title:  Autopsy: Infectious and Serious Communicable Diseases
Nbr:  177  Title:  Letters to the Editor Emergence of a novel coronavirus causing respiratory illness from Wuhan, China Declaration of Competing Interest
Nbr:  178  Title:  m-Health in Public Health Practice: A Constellation of Current Evidence
Nbr:  179  Title:  Personal View Disease X: accelerating the development of medical countermeasures for the next pandemic
Nbr:  180  Title:  Automated methods for antibiotic susceptibility testing P441 Vancomycin reformulation in a Microscan Dried Overnight Panel: a multicentre evaluation with Gram-positive cocci including VRSA P442 Direct identification and susceptibility testing of Gram-positive cocci from positive Bactec blood cultures with BD Phoenix Automated Microbiology System P445 Evaluation of identification and antimicrobial susceptibility testing of bacterial pathogens by VITEK 2 Compact System P446 Evaluation of the Vitek-2 system using AST-N020 y AST-N041 cards for susceptibility testing of beta-lactam-resistant Escherichia coli and Klebsiella pneumoniae strains of clinical origin P447 Susceptibility testing of unusual species of Enterobacteriaceae: comparison of disk diffusion, Vitek 2, and broth microdilution P448 Evaluation of new VITEK 2 AST cards for detection of ESBL mediated resistance in E. coli and Klebsiella spp. P449 Detection of ESBL mediated resistance in Enterobacter spp. by using new VITEK2 AST cards and advanced expert system P451 Evaluation of the VITEK 2Ò ESBL test in detecting ESBL-positive clinical Escherichia coli and Klebsiella pneumoniae isolates
Nbr:  181  Title:  Influenza vaccine coverage rates and perceptions on vaccination in South Korea
Nbr:  182  Title:  Nanoparticle-based vaccines: opportunities and limitations
Nbr:  184  Title:  Wildlife parasites in a One Health world
Nbr:  185  Title:  Pretravel Considerations for Non-vaccine-Preventable Travel Infections
Nbr:  186  Title:  Viral Pneumonias
Nbr:  187  Title:  A Novel Molecular Microbiologic Technique for the Rapid Diagnosis of Microbial Invasion of the Amniotic Cavity and Intra- Amniotic Infection in Preterm Labor with Intact Membranes NIH Public Access
Nbr:  188  Title:  Sterile and Microbial-associated Intra-amniotic Inflammation in Preterm Prelabor Rupture of Membranes HHS Public Access
Nbr:  189  Title:  THE NATURE AND CLASSIFICATION OF VIRUSES OF MAN
Nbr:  191  Title:  Other herbs and spices: mango ginger to wasabi
Nbr:  192  Title:  Evolutionary Medicine: A Powerful Tool for Improving Human Health
Nbr:  193  Title:  Pandemic H1N1 2009 in Neonates
Nbr:  194  Title:  Loop-mediated isothermal amplifi cation (LAMP): a rapid, accurate, and cost-effective diagnostic method for infectious diseases
Nbr:  198  Title:  INFECTION CONTROL CHALLENGES IN CHILD-CARE CENTERS
Nbr:  199  Title:  An early report from newly established laboratory- based influenza surveillance in Lao PDR
Nbr:  200  Title:  A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition Animal Models for Vaccine Research 721 Preclinical Toxicology of Vaccines 1 Edelman [3] and Griffin [2] classified adjuvants into two groups
Nbr:  201  Title:  Childhood Infectious Diseases: Overview
Nbr:  202  Title:  Surveillance of Infectious Diseases
Nbr:  203  Title:  The art of partnerships for vaccines q,qq
Nbr:  204  Title:  Clinical Manifestations and Laboratory Diagnosis of Ebola Virus Infection Chapter Outline
Nbr:  205  Title:  Viral Infections in Patients with Acute Respiratory Infection in Northwest of Iran 1
Nbr:  207  Title:  Communicable Diseases Learning Objectives
Nbr:  208  Title:  The experiences of health care workers employed in an Australian intensive care unit during the H1N1 Influenza pandemic of 2009: A phenomenological study
Nbr:  209  Title:  Materno-fetal transmission of human coronaviruses: a prospective pilot study
Nbr:  210  Title:  Evaluation of clinical applicability of reverse transcription-loop-mediated isothermal amplification assay for detection and subtyping of Influenza A viruses
Nbr:  212  Title:  King Abdulaziz Medical City, Ministry of National Guard Health Affairs
Nbr:  214  Title:  Letters to the Editor Emergence of a novel coronavirus causing respiratory illness from Wuhan, China Declaration of Competing Interest
Nbr:  215  Title:  2009 H1N1 Influenza: A Twenty-First Century Pandemic With Roots in the Early Twentieth Century
Nbr:  216  Title:  2007 guideline for isolation precautions: preventing transmission of infectious agents in health care settings
Nbr:  219  Title:  Innovations in HIV-1 Vaccine Design
Nbr:  220  Title:  Chapter 16 The Clinician and the Microbiology Laboratory
Nbr:  221  Title:  Neuraxial labor analgesia in an obese parturient with influenza A H1N1
Nbr:  222  Title:  Detection of hepatitis E virus and other livestock-related pathogens in Iowa streams
Nbr:  223  Title:  We can do betterdimproving the health of the American people
Nbr:  225  Title:  Use of Obstetric Practice Web Sites to Distribute Zika Virus Information to Pregnant Women During a Zika Virus Outbreak
Nbr:  226  Title:  SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics
Nbr:  227  Title:  A Downward Trend of the Ratio of Influenza RNA Copy Number to Infectious Viral Titer in Hospitalized Influenza A-Infected Patients
Nbr:  228  Title:  UK newspapers' representations of the 2009e10 outbreak of swine flu: one health scare not over-hyped by the media?
Nbr:  229  Title:  Travellers and influenza: risks and prevention
Nbr:  231  Title:  INQUIRY: The Journal of Health Care Organization, Provision, and Financing
Nbr:  232  Title:  Safety of Tdap vaccine in pregnant women: an observational study
Nbr:  233  Title:  Nucleosides for the treatment of respiratory RNA virus infections Introduction to respiratory infections caused by RNA viruses
Nbr:  234  Title:  vaccines) in public health emergencies
Nbr:  235  Title:  H1N1 influenza pandemic in Italy revisited: has the willingness to get vaccinated suffered in the long run?
Nbr:  236  Title:  Emerging Microbes and Infections (2012) 1, e46
Nbr:  237  Title:  Prevalence of diabetes in the 2009 influenza A (H1N1) and the Middle East respiratory syndrome coronavirus: a systematic review and meta-analysis
Nbr:  238  Title:  Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/)
Nbr:  239  Title:  R E V I E W Immunoinformatics and Vaccine Development: An Overview
Nbr:  240  Title:  2018 recommendations for the management of community acquired pneumonia
Nbr:  242  Title:  Severe virus influenza A H1N1 related pneumonia and community-acquired pneumonia: differences in the evolution
Nbr:  243  Title:  Send Orders of Reprints at bspsaif@emirates.net.ae 104 The Open Virology Journal
Nbr:  244  Title:  Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections
Nbr:  245  Title:  Non-invasive ventilation in a pregnancy with severe pneumonia
Nbr:  246  Title:  Evolution of information-driven HIV/AIDS policies in China
Nbr:  248  Title:  Neutralizing antibody responses to enterovirus and adenovirus in healthy adults in China
Nbr:  249  Title:  Poster presentations Risky behavior among MSM in Armenia Intensified case findings: a retrospective analysis among adult PLHIV TB results in Eggon LGA of Nasarawa state, Nigeria
Nbr:  250  Title:  Emerging Microbes and Infections (2012) 1, e31
Nbr:  251  Title:  World Journal of Clinical Cases CASE REPORT 222 Duodenal gangliocytic paraganglioma with lymph node metastases: A case report and comparative review of 31 cases 234 Bilateral renal cortical necrosis associated with smoking synthetic cannabinoids 238 Effect of double platinum agents, combination of miriplatin-transarterial oily chemoembolization and cisplatin-hepatic arterial infusion chemotherapy, in patients with hepatocellular carcinoma: Report of two cases Immunophenotypic signature of primary glioblastoma multiforme: A case of extended progression free survival 254 Ileocolic intussusception caused by a lipoma in an adult EDITORS FOR THIS ISSUE Proofing Editor-in-Chief: ABOUT COVER AIM AND SCOPE INDExING/ABSTRACTING Editorial Board Member of World Journal of Clinical Cases
Nbr:  252  Title:  Title page Association between syphilis prevalence and age: an analysis of surveillance data among blood donors in southern China, 2014-2017
Nbr:  253  Title:  Birth Defects Data from Surveillance Hospitals in Hubei Prov- ince, China, 200l -2008
Nbr:  254  Title:  Clinical and pathological characteristics of 2019 novel coronavirus disease (COVID-19): a systematic reviews
Nbr:  255  Title:  The infection evidence of SARS-COV-2 in ocular surface： a single-center cross-sectional study Funding Sources
Nbr:  256  Title:  Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study
Nbr:  257  Title:  Mechanistic insights into Zika virus NS3 helicase inhibition by Epigallocatechin-3-gallate
Nbr:  258  Title:  The Effect of Aqueous Extract of Glycyrrhiza glabra on Herpes Simplex Virus 1
Nbr:  259  Title:  viruses Hepatitis E Virus Replication
Nbr:  260  Title:  viruses Hepatitis E Virus Drug Development
Nbr:  261  Title:  Rapid development of vaccines against emerging pathogens: The replication-deficient simian adenovirus platform technology
Nbr:  262  Title:  Citation: A Peptide-Based Virus Inactivator Protects Male Mice Against Zika Virus-Induced Damage of Testicular Tissue
Nbr:  263  Title:  Surveillance and response systems for elimination of tropical diseases: summary of a thematic series in Infectious Diseases of Poverty
Nbr:  264  Title:  ARTICLE Safety and efficacy of ChAdOx1 RVF vaccine against Rift Valley fever in pregnant sheep and goats
Nbr:  265  Title:  Pertussis in infants: an underestimated disease
Nbr:  266  Title:  A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus
Nbr:  267  Title:  Reassuring and managing patients with concerns about swine flu: Qualitative interviews with callers to NHS Direct
Nbr:  268  Title:  Hospitalization Risk Due to Respiratory Illness Associated with Genetic Variation at IFITM3 in Patients with Influenza A(H1N1)pdm09 Infection: A Case-Control Study
Nbr:  269  Title:  Zika Virus: Where Is the Treatment?
Nbr:  270  Title:  Public views of the uk media and government reaction to the 2009 swine flu pandemic
Nbr:  271  Title:  Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity
Nbr:  272  Title:  Serum 25-Hydroxyvitamin D and the Incidence of Acute Viral Respiratory Tract Infections in Healthy Adults
Nbr:  273  Title:  Neutralization Interfering Antibodies: A "Novel" Example of Humoral Immune Dysfunction Facilitating Viral Escape?
Nbr:  274  Title:  Detection of Zika virus using reverse- transcription LAMP coupled with reverse dot blot analysis in saliva
Nbr:  275  Title:  Molecular Sciences Review Advances in Zika Virus-Host Cell Interaction: Current Knowledge and Future Perspectives
Nbr:  276  Title:  R E V I E W Open Access 'The Microbiome and the Pathophysiology of Asthma'
Nbr:  277  Title:  Anticipation and response: pandemic influenza in Malawi, 2009
Nbr:  278  Title:  Rabies-based vaccine induces potent immune responses against Nipah virus
Nbr:  279  Title:  pharmaceuticals Lipid Metabolism as a Source of Druggable Targets for Antiviral Discovery against Zika and Other Flaviviruses
Nbr:  280  Title:  Epidemiology and Infection Risk factors and patterns of household clusters of respiratory viruses in rural Nepal
Nbr:  281  Title:  ESICM LIVES 2016: part one Oral Sessions. ARDS: CLINICAL STUDIES A1 Identification of distinct endophenotypes in patients with acute respiratory distress syndrome by unbiased cluster analysis, and their association with mortality
Nbr:  282  Title:  Cell Repertoire Analysis Identifies New Antigenic Domains on Glycoprotein B of Human Cytomegalovirus which Are Target of Neutralizing Antibodies
Nbr:  283  Title:  Therapeutic antibodies for infectious diseases
Nbr:  285  Title:  Temporal patterns and geographic heterogeneity of Zika virus (ZIKV) outbreaks in French Polynesia and Central America
Nbr:  286  Title:  Deep sequencing of primary human lung epithelial cells challenged with H5N1 influenza virus reveals a proviral role for CEACAM1 OPEN
Nbr:  287  Title:  Vaccination against Paediatric Respiratory Pathogens
Nbr:  288  Title:  biomolecules Cyclodextrins: Emerging Medicines of the New Millennium
Nbr:  289  Title:  Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019- nCoV) outbreak
Nbr:  290  Title:  Influenza A (H1N1) and Other Viruses in Patients Hospitalized with Respiratory Illness
Nbr:  291  Title:  BMC Public Health
Nbr:  292  Title:  Outcomes of Influenza A(H1N1)pdm09 Virus Infection: Results from Two International Cohort Studies
Nbr:  293  Title:  The Placental Protein Syncytin-1 Impairs Antiviral Responses and Exaggerates Inflammatory Responses to Influenza
Nbr:  294  Title:  Vaccines, inspiring innovation in health q
Nbr:  295  Title:  Malaria vaccines: high-throughput tools for antigen discovery with development potential Vacunas contra la malaria: estrategias de alto rendimiento para el descubrimiento de antígenos con potencial para su desarrollo Epidemiological importance of malaria
Nbr:  296  Title:  Vaccines, inspiring innovation in health q
Nbr:  297  Title:  Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype- Specific Neutralizing Antibody Responses
Nbr:  298  Title:  Communicating uncertainty -how Australian television reported H1N1 risk in 2009: a content analysis
Nbr:  299  Title:  Epidemiology, Seasonality and Treatment of Hospitalized Adults and Adolescents with Influenza in Jingzhou
Nbr:  300  Title:  Vaccination with recombinant adenovirus expressing multi-stage antigens of Toxoplasma gondii by the mucosal route induces higher systemic cellular and local mucosal immune responses than with other vaccination routes
Nbr:  301  Title:  Articles Progress and challenges in maternal health in western China: a Countdown to 2015 national case study
Nbr:  302  Title:  Hepatitis E Virus Cysteine Protease Has Papain Like Properties Validated by in silico Modeling and Cell-Free Inhibition Assays
Nbr:  303  Title:  Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?
Nbr:  305  Title:  National inventory of emergency departments in Singapore
Nbr:  306  Title:  Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity
Nbr:  307  Title:  Transfer of Anti-Rotavirus Antibodies during Pregnancy and in Milk Following Maternal Vaccination with a Herpes Simplex Virus Type-1 Amplicon Vector
Nbr:  308  Title:  Promoting influenza prevention for elderly people in Hong Kong using health action process approach: study protocol
Nbr:  309  Title:  The impact on neonatal mortality of shifting childbirth services among levels of hospitals: Taiwan's experience
Nbr:  310  Title:  Host-Virus Protein Interaction Network Reveals the Involvement of Multiple Host Processes in the Life Cycle of Hepatitis E Virus
Nbr:  311  Title:  Responding to the Pandemic of Falsified Medicines
Nbr:  312  Title:  Tropical Medicine and Infectious Disease Future Pandemic Influenza Virus Detection Relies on the Existing Influenza Surveillance Systems: A Perspective from Australia and New Zealand
Nbr:  313  Title:  Impact of Middle East Respiratory Syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome
Nbr:  314  Title:  Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Nbr:  315  Title:  A Meta-Analysis of the Association between Gender and Protective Behaviors in Response to Respiratory Epidemics and Pandemics Introduction Motivation and overview
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Nbr:  317  Title:  Risk Perception, Preventive Behaviors, and Vaccination Coverage in the Korean Population during the 2009- 2010 Pandemic Influenza A (H1N1): Comparison between High-Risk Group and Non-High-Risk Group
Nbr:  319  Title:  Risk Factors for Death from Influenza A (H1N1)pdm09, State of São Paulo, Brazil, 2009
Nbr:  320  Title:  Pathogenesis of bacterial infections A1 The outcome of patients with recurrent versus non-recurrent pneumococcal meningitis in a tertiary health-care hospital in Bucharest
Nbr:  321  Title:  Associated Severe Acute Respiratory Illness in South Africa Using a Rapid Assessment Methodology
Nbr:  322  Title:  Maternal Influenza Immunization and Reduced Likelihood of Prematurity and Small for Gestational Age Births: A Retrospective Cohort Study
Nbr:  323  Title:  Mortality estimates among adult patients with severe acute respiratory infections from two sentinel hospitals in southern Arizona, United States, 2010-2014
Nbr:  324  Title:  Discovery and Genomic Characterization of a Novel Ovine Partetravirus and a New Genotype of Bovine Partetravirus
Nbr:  325  Title:  Clinical outcomes among hospital patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection
Nbr:  326  Title:  Results From the First Six Years of National Sentinel Surveillance for Influenza in Kenya
Nbr:  327  Title:  Author Contributions
Nbr:  328  Title:  Current and Novel Approaches in Influenza Management
Nbr:  329  Title:  Rational Design of Zika Virus Subunit Vaccine with Enhanced Efficacy
Nbr:  330  Title:  When could human challenge trials be deployed to combat emerging infectious diseases? Lessons from the case of a Zika virus human challenge trial
Nbr:  331  Title:  High Burden of Non-Influenza Viruses in Influenza-Like Illness in the Early Weeks of H1N1v Epidemic in France
Nbr:  332  Title:  CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice
Nbr:  333  Title:  Rapid Detection Strategies for the Global Threat of Zika Virus: Current State, New Hypotheses, and Limitations OVERVIEW: WHAT IS ZIKA AND HOW DID IT BECOME EPIDEMIC?
Nbr:  334  Title:  "Epidemiology and aetiology of influenza-like illness among households in metropolitan Vientiane, Lao PDR": A prospective, community-based cohort study
Nbr:  335  Title:  Environmental Research and Public Health Article Infections in Healthcare Workers in Germany-22-Year Time Trends †
Nbr:  336  Title:  Trend analysis of mortality rates and causes of death in children under 5 years old in Beijing, China from 1992 to 2015 and forecast of mortality into the future: an entire population-based epidemiological study
Nbr:  337  Title:  The Mechanism of Action of Ursolic Acid as a Potential Anti-Toxoplasmosis Agent, and Its Immunomodulatory Effects
Nbr:  338  Title:  Virology Journal Macrophages and cytokines in the early defence against herpes simplex virus
Nbr:  339  Title:  Mutagenic Effects of Ribavirin on Hepatitis E Virus-Viral Extinction versus Selection of Fitness-Enhancing Mutations
Nbr:  340  Title:  Citation: Crystal Structure of Refolding Fusion Core of Lassa Virus GP2 and Design of Lassa Virus Fusion Inhibitors
Nbr:  341  Title:  Predicted protein interactions of IFITMs may shed light on mechanisms of Zika virus-induced microcephaly and host invasion [version 2; referees: 2 approved, 1 approved with reservations, 1 not approved] Referee Status: Invited Referees version 2 , University of Amendments from Version 1
Nbr:  342  Title:  The burden and clinical manifestation of hospitalized influenza among different pediatric age-groups in the tropics
Nbr:  343  Title:  Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses
Nbr:  344  Title:  Specialty Grand challenge in pediatric infectious diseases
Nbr:  345  Title:  Potent Inhibition of Zika Virus Replication by Aurintricarboxylic Acid
Nbr:  346  Title:  Update on the angiotensin converting enzyme 2-angiotensin (1-7)-Mas receptor axis: fetal programing, sex differences, and intracellular pathways
Nbr:  347  Title:  Opinion piece
Nbr:  348  Title:  Influenza virus-related critical illness: pathophysiology and epidemiology
====================================================================================================

</code>

## kNN for Document Similarity
In this section we learn a kNN to retrieve documents which are most similar (contain) the words given in search.
With topic modelling, we have topics against each document, therefore we perform the next step of working out most similar papers._____no_output_____

<code>
# revisit the df_covid we created
display(df_covid)_____no_output_____# we compute the most common words occuring in these 33375 documents
def compute_tokens_after_cleaning(sentences):
    wordcount = {}
    for ix in range(len(sentences['title'])):
        full_text = ''.join(x for x in sentences['sents'][ix])
        tokens = prepare_text_for_lda(full_text)
        for word in tokens:
            if word not in wordcount:
                wordcount[word] = 1
            else:
                wordcount[word] += 1
    return wordcount
wordcount = compute_tokens_after_cleaning(relevant_sentences)
print(wordcount){'Recommendations': 2, 'place': 14, 'pregnant': 3389, 'woman': 3601, 'fetus': 142, 'expose': 54, 'radiation': 3, 'mother': 70, 'finding': 4, 'understandable': 1, 'member': 21, 'high-risk': 57, 'group': 223, 'individual': 148, 'chronic': 152, 'health': 198, 'conditions': 96, 'among': 236, 'pilgrim': 20, 'secondly': 2, 'previous': 36, 'report': 201, 'indicate': 46, 'pdm09': 23, 'infection': 657, 'associate': 115, 'mortality': 170, 'rates': 78, 'finally': 4, 'instructions': 2, 'given': 69, 'contact': 46, 'hygiene': 3, 'respiratory': 134, 'etiquette': 1, 'immunization': 55, 'visit': 30, 'week': 48, 'month': 96, 'incidence': 41, 'characteristic': 24, 'describe': 45, 'Twenty-five': 2, 'infect': 167, 'pregnancy': 323, 'compare': 98, 'contract': 4, 'rhinovirus': 11, 'syncytial': 5, 'virus': 222, 'intervention': 20, 'reduce': 57, 'febrile': 15, 'illness': 132, 'potential': 96, 'decrease': 42, 'adverse': 50, 'birth': 112, 'outcome': 99, 'developing': 37, 'country': 69, 'Illness': 2, 'death': 122, 'receive': 92, 'greater': 35, 'appreciation': 1, 'globally': 2, 'following': 42, 'pandemic': 110, 'influenza': 320, 'outbreak': 88, 'Pregnancy': 13, 'know': 49, 'immunomodulating': 1, 'effect': 22, 'elevated': 15, 'complication': 98, 'seasonal': 37, 'study': 427, 'clinical': 162, 'rural': 17, 'population': 209, 'South': 12, 'obtain': 23, 'consecutive': 3, 'community-based': 2, 'randomize': 9, 'control': 97, 'trial': 63, 'year-round': 1, 'vaccination': 174, 'Sarlahi': 1, 'Nepal3': 1, 'represent': 13, 'case': 143, 'Other': 10, 'detect': 31, 'cohort': 37, 'coronavirus': 20, 'parainfluenza': 3, 'bocavirus': 3, 'adenovirus': 2, 'Table': 27, 'Among': 26, 'median': 14, 'gestational': 28, 'disease': 464, 'overall': 16, 'cough': 14, 'common': 47, 'symptom': 102, 'except': 13, 'rhinorrhea/nasal': 1, 'congestion': 1, 'Twelve': 8, 'Overall': 6, 'commonly': 16, 'pathogen': 36, 'relatively': 19, 'contrast': 13, 'literature': 7, 'demonstrate': 50, 'severe': 239, 'Rates': 1, 'hypertension': 7, 'maternal': 103, 'smoking': 8, 'alcohol': 4, 'found': 75, 'difference': 28, 'index': 9, 'without': 56, 'conduct': 31, 'type': 6, 'setting': 19, 'particularly': 77, 'notable': 3, 'presentation': 9, 'differ': 7, 'region': 24, 'world': 8, 'household': 17, 'density': 1, 'malnutrition': 2, 'indoor': 3, 'pollution': 1, 'newborn': 83, 'infant': 188, 'area': 49, 'target': 76, 'specifically': 16, 'example': 54, 'patient': 322, 'lab-confirmed': 1, 'acute': 74, 'syndrome': 35, 'United': 35, 'States': 34, 'Specific': 2, 'concern': 62, 'obstetrician-gynecologists': 4, 'include': 324, 'issue': 40, 'relevant': 5, 'address': 19, 'Because': 25, 'ribavirin': 36, 'teratogenic': 31, 'embryocidal': 1, 'animal': 50, 'recommend': 166, 'treatment': 180, 'Although': 75, 'several': 36, 'number': 66, 'small': 38, 'permit': 3, 'definitive': 4, 'conclusion': 16, 'whether': 29, 'nonpregnant': 119, 'perinatal': 15, 'transmission': 111, 'large': 24, 'series': 18, 'healthcare': 35, 'worker': 56, 'admit': 25, 'public': 56, 'hospital': 48, 'Seven': 4, 'first': 102, 'trimester': 122, 'second': 44, 'third': 72, 'evaluate': 33, 'likely': 66, 'require': 85, 'admission': 25, 'intensive': 15, 'experience': 52, 'renal': 23, 'failure': 40, 'disseminate': 10, 'intravascular': 4, 'coagulopathy': 4, 'subject': 29, 'Followup': 1, 'information': 56, 'liveborn': 1, 'There': 50, 'mainland': 1, 'China': 26, '42,43': 1, 'Notably': 2, 'person': 123, 'laboratory-confirmed': 14, 'During': 28, 'nosocomial': 1, 'spread': 10, 'play': 2, 'important': 65, 'implication': 9, 'obstetric': 13, 'provide': 76, 'urgent': 5, 'medical': 97, '24-hour': 1, 'basis': 16, 'primarily': 16, 'healthy': 86, 'enormous': 1, 'basic': 4, 'principle': 7, 'response': 96, 'Toronto': 1, 'keeping': 1, 'potentially': 20, 'infectious': 45, 'avoid': 51, 'exposure': 78, 'mosquito': 10, 'wearing': 5, 'protective': 13, 'clothing': 3, 'outdoor': 2, 'activity': 23, 'feeding': 6, 'times': 18, 'usually': 20, 'Safety': 6, 'come': 5, 'largely': 1, 'toxicity': 16, 'malaria': 53, 'Thailand': 2, 'apply': 16, 'daily': 12, 'serious': 55, 'neonatal': 34, 'effects': 89, 'unexplained': 1, 'fever': 60, 'mental': 5, 'status': 23, 'change': 40, 'meningitis': 6, 'encephalitis': 1, 'flaccid': 1, 'paralysis': 2, 'consider': 90, 'diagnosis': 24, 'sample': 60, 'serum': 44, 'cerebrospinal': 2, 'fluid': 24, 'However': 75, 'screening': 44, 'asymptomatic': 45, 'registry': 7, 'since': 13, 'tracking': 2, 'anthrax': 9, 'attack': 20, 'recommendation': 77, 'implement': 13, 'postexposure': 6, 'prophylaxis': 48, 'regimen': 24, 'need': 42, 'develop': 89, 'rapidly': 8, 'Doxycycline': 1, 'caution': 6, 'cause': 127, 'fetal': 70, 'toxic': 7, 'defective': 2, 'dental': 2, 'enamel': 4, 'depress': 4, 'growth': 15, 'addition': 41, 'doxycycline': 11, 'infrequently': 3, 'hepatic': 8, 'necrosis': 4, 'risk': 67, 'balance': 3, 'appropriate': 36, 'meantime': 1, 'Department': 5, 'Defense': 2, 'policy': 14, 'continue': 13, 'exclude': 37, 'program': 37, 'African-Americans': 2, 'Asians': 2, 'immunocompromised': 103, 'higher': 121, 'others': 23, 'recognize': 14, 'critical': 22, 'arise': 11, 'regard': 40, 'unborn': 10, 'child': 393, 'Questions': 2, 'course': 37, 'labor': 13, 'delivery': 66, 'breastfeed': 15, 'unanswered': 2, 'emerge': 26, 'often': 31, 'collect': 27, 'surveillance': 32, 'occur': 72, 'little': 14, 'natural': 8, 'history': 30, 'particular': 36, 'Despite': 9, 'ciprofloxacin': 9, 'highrisk': 5, 'Monitoring': 3, 'become': 40, 'integral': 2, 'investigation': 14, 'general': 52, 'guideline': 32, 'exist': 14, 'pre-event': 2, 'rather': 5, 'cobbling': 1, 'together': 9, 'vulnerable': 51, 'emergency': 21, 'review': 30, 'clear': 15, 'susceptible': 60, 'non-pregnant': 118, 'track': 2, 'miscarriage': 10, 'elective': 2, 'abortion': 25, 'rectal': 2, 'vaginal': 18, 'specimen': 9, 'gestation': 34, 'positive': 43, 'retrospective': 10, 'CA-MRSA': 1, 'Parkland': 1, 'Memorial': 1, 'Hospital': 18, 'Dallas': 1, 'Texas': 3, 'show': 86, 'evidence': 80, 'increase': 249, 'chorioamnionitis': 3, 'sepsis': 10, 'Ethical': 1, 'pre-natal': 1, 'testing': 49, 'family': 36, 'dementia-associated': 1, 'prion': 1, 'sensitive': 4, 'method': 19, 'determine': 20, 'level': 79, 'biological': 6, 'material': 6, 'discriminate': 2, 'normal': 22, 'various': 19, 'trophoblastic': 1, '3Galb1': 1, '4GlcNAcb1': 1, 'sugar': 1, 'moiety': 1, 'could': 51, 'invasive': 12, 'choriocarcinoma': 1, 'hydatidiform': 1, 'vaccine': 375, 'extra': 2, 'ingredient': 1, 'widely': 13, 'Europe': 9, 'never': 4, 'safety': 91, 'young': 100, 'Disease': 22, 'Keynote': 1, '1-How': 2, 'identify': 47, 'prepare': 5, 'Discussion': 2, 'global': 12, 'biosurveillance': 2, 'enterprise': 2, 'infrastructure': 3, 'improve': 26, 'better': 12, 'support': 57, 'biopreparedness': 1, '2-How': 1, 'universal': 14, 'assess': 10, 'neglect': 1, 'elderly': 125, 'growing': 2, 'congenital': 72, 'abnormality': 20, 'demise': 2, 'Brasil': 2, 'result': 111, 'microcephaly': 37, 'developmental': 8, 'disorder': 28, 'major': 18, 'problem': 21, 'larger': 8, 'numbers': 14, 'SARS-CoV': 17, 'refine': 1, 'infectioncontrol': 1, 'strategy': 44, 'sound': 3, 'manage': 7, 'future': 20, 'thalidomide': 6, 'antinauseant': 1, 'sleeping': 2, 'Canada': 9, 'Australia': 6, '1960s': 1, 'approve': 19, 'significance': 6, 'findings': 34, 'contraindicate': 44, 'asthma': 62, 'pulmonary': 24, 'cardiovascular': 17, 'system': 46, 'underlie': 53, 'diabetes': 55, 'dysfunction': 4, 'hemoglobinopathy': 2, 'suspect': 28, 'immunodeficiency': 19, 'immunosuppressive': 14, 'therapy': 76, 'adolescent': 14, 'aspirin': 5, 'salicylate': 1, 'Guillain-Barré': 4, 'hypersensitivity': 2, 'contrary': 2, 'IgG-AECA': 1, 'significantly': 22, 'Taken': 2, 'physiological': 8, 'tolerance': 9, 'pathogenic': 4, 'impair': 11, 'reproductive': 19, 'function': 23, 'frequently': 9, 'Third': 7, 'morbidity': 45, 'select': 18, 'adult': 145, 'experiment': 3, 'director': 2, 'Recombinant': 2, 'Advisory': 10, 'Committee': 10, 'local': 20, 'institutional': 2, 'biosafety': 2, 'committee': 3, 'initiation': 5, 'Section': 2, 'III-A-1': 1, 'III-A-1-a': 1, 'Starting': 2, 'August': 5, 'non-smoking': 1, 'enrol': 22, 'GRAPHS': 2, 'antenatal': 35, 'period': 45, 'comprise': 6, 'window': 5, 'susceptibility': 22, 'reduction': 17, 'effective': 38, 'Individuals': 2, 'assistance': 2, 'confine': 1, 'wheel-chairs': 1, 'dependent': 3, 'crutch': 1, 'cane': 1, 'walker': 1, 'recover': 5, 'surgery': 1, 'significant': 48, 'hearing': 2, 'sight': 1, 'impairment': 9, 'extremely': 4, 'overweight': 2, 'incapacitate': 1, 'serosurvey': 1, 'community-wide': 1, 'Colorado': 1, 'antiretroviral': 15, 'drug': 48, 'HIV-infected': 21, 'substantially': 2, 'Groups': 7, 'listeriosis': 13, 'neonate': 47, 'immune-compromised': 5, 'percentage': 4, 'cell': 28, 'inversely': 3, 'correlate': 4, 'values': 8, 'observe': 47, 'phase': 27, 'hormone': 9, 'amenorrhea': 1, 'pretravel': 1, 'consultation': 4, 'cogent': 1, 'argument': 3, 'travel': 27, 'postponement': 1, 'planning': 21, 'malarial': 2, 'Hepatitis': 12, 'Immunization': 20, 'Travel': 2, 'Medicine': 3, 'life-threatening': 5, 'enhancement': 5, 'document': 24, 'previously': 19, 'candidate': 20, 'protein-based': 1, 'tolerate': 8, 'Girard': 1, 'Interestingly': 3, 'vaccinate': 32, 'PFP-2': 6, 'anti-F': 1, 'antibody': 59, 'persistently': 2, 'suggest': 82, 'another': 10, 'single': 8, 'usage': 4, 'zidovudine': 8, 'decade': 10, 'peripartum': 3, 'three-part': 2, 'availability': 7, 'size': 2, 'one-third': 5, 'sub-Saharan': 8, 'estimate': 35, 'agent': 27, 'difficult': 10, 'specific': 44, 'ensure': 22, 'intake': 7, 'recently': 27, 'innovation': 2, 'fortification': 3, 'sachet': 1, 'multiple-micronutrient': 1, 'Sprinkles': 1, 'adapt': 1, 'self-limiting': 10, 'nature': 4, 'subpopulation': 6, 'reach': 15, 'progress': 7, 'chronicity': 2, 'antiviral': 47, 'option': 17, 'Current': 8, 'therapeutics': 5, 'treat': 64, 'Interferon-α': 1, 'Acute': 9, 'liver': 44, 'preexist': 5, 'fatal': 16, 'onset': 22, 'within': 43, 'straightforward': 2, 'viral': 66, 'loads': 3, 'self-limited': 2, 'hepatitis': 71, 'century': 1, 'promotion': 4, 'vital': 2, 'promote': 12, 'preventive': 15, 'HIV-positive': 10, 'backsliding': 1, 'practice': 10, 'reappearance': 1, 'sexually': 6, 'transmit': 20, 'thought': 7, 'Vector': 1, 'factor': 50, 'pneumonia': 128, 'chronically': 2, 'Background': 2, 'rhinitis': 3, 'condition': 17, 'affect': 66, '18Y30': 1, 'relationship': 10, 'Resonant': 1, 'Frequency': 1, 'force': 2, 'expiratory': 1, 'volume': 4, 'capacity': 7, 'latter': 3, 'people': 149, 'blood': 54, 'pressure': 8, 'intense': 3, 'viremia': 4, 'parvovirus': 3, 'particle': 2, 'predispose': 8, 'cross-placental': 1, 'sensor': 1, 'test': 40, 'using': 34, 'standard': 11, 'These': 47, 'observation': 10, 'ought': 1, 'prevent': 63, 'Indeed': 2, 'Centers': 16, 'Control': 21, 'vention': 1, 'chemoprophyl': 1, 'either': 28, 'oseltamivir': 18, 'zanamivir': 6, 'uenza': 37, 'Denise': 1, 'Jamieson': 2, 'colleague': 11, 'highlight': 9, 'Prevention': 18, 'advice': 11, 'poor': 3, 'H1N1-aff': 2, 'ected': 2, 'couple': 3, 'rapid': 9, 'access': 23, 'quantitative': 4, 'reverse-transcriptase': 1, 'early': 44, 'institution': 6, 'start': 12, 'Singapore': 2, 'Between': 5, 'diagnose': 18, 'National': 13, 'University': 8, 'nationwide': 3, 'timely': 2, 'attention': 17, 'recourse': 1, 'Subsequently': 4, 'campaign': 10, 'begin': 9, 'HTLV-1': 4, 'mother-tochild': 2, 'Weaver': 1, 'manifestation': 6, 'humans': 27, 'impact': 31, 'hunger': 1, 'famine': 1, 'gender': 4, 'whole': 5, 'industrialize': 1, 'anemia': 14, 'percent': 23, 'Latin': 3, 'America': 6, 'India': 13, 'Iron-folate': 1, 'supplementation': 9, 'grateful': 1, 'secret': 1, 'clinician': 5, 'protect': 48, 'caregiver': 3, 'handle': 7, 'serve': 6, 'role': 1, 'conducting': 4, 'guidance': 14, 'diagnosing': 2, 'establish': 19, 'designing': 3, 'education': 9, 'resource': 10, 'assist': 4, 'obstetriciangynecologists': 1, 'influenzarelated': 2, 'years': 168, 'Unfortunately': 5, 'getting': 3, 'prominence': 1, 'influenza-associated': 4, 'hospitalization': 43, 'spring': 2, 'striking': 3, 'realize': 2, 'reluctant': 3, 'medication': 41, 'jar': 1, 'newly': 9, 'acquire': 26, 'decline': 6, 'safe': 4, 'injection': 9, 'Mortality': 9, 'approximately': 13, 'Anemia': 1, 'define': 17, 'World': 13, 'Health': 51, 'Organization': 13, 'hemoglobin': 2, 'male': 6, 'alter': 12, 'efficacy': 23, 'tissue': 21, 'oxygen': 19, 'supply': 3, 'constitute': 5, 'prolongation': 1, 'quality': 13, 'Public': 9, 'Service': 2, 'cesarean': 11, 'HIV-1-infected': 5, 'peripheral': 5, '1,000': 2, 'copies/mL': 1, 'irrespective': 2, 'International': 3, 'Maternal': 10, 'Pediatric': 3, 'Adolescent': 1, 'Clinical': 7, 'Trials': 2, 'Network': 3, 'IMPAACT': 1, 'Protocol': 2, 'formerly': 2, 'PACTG': 1, 'ongoing': 10, 'multi-center': 1, 'observational': 5, 'Puerto': 1, 'amniocentesis': 3, 'HIV-1infected': 1, 'inform': 15, 'choice': 5, 'relate': 33, 'benefit': 61, 'prevention': 39, 'mother-to-child': 10, 'HIV-1': 4, 'Saudi': 17, 'Ministry': 12, 'uenza-ie': 1, 'younger': 23, 'immunosuppressed': 30, 'HIV/AIDS': 8, 'heart': 43, 'According': 10, 'current': 26, 'yearly': 3, 'MERS-CoV': 18, 'postpone': 18, 'Umrah': 9, 'older': 64, 'kidney': 25, 'autoimmune': 3, 'immune': 85, 'ciency': 1, 'taking': 13, 'malignant': 5, 'terminal': 13, 'Given': 15, 'pathogenesis': 6, 'tropism': 1, 'publicdespecially': 1, 'fetusesdfrom': 1, 'childbearing': 23, 'infants/children': 1, 'ethical': 7, 'unknown': 33, 'possible': 30, 'inactivate': 25, 'perhaps': 7, 'dose': 20, 'durable': 3, 'long-lasting': 2, 'vaccineinduced': 1, 'immunity': 34, 'inadvertent': 6, 'Fifth': 1, 'human': 53, 'challenge': 26, 'development': 68, 'debate': 3, 'incarcerate': 1, 'engage': 4, 'behaviour': 3, 'dangerous': 4, 'Severe': 11, 'although': 32, 'military': 3, 'inadvertently': 7, 'defect': 40, 'paediatric': 5, 'immunological': 3, 'CMV-specific': 3, 'avidity': 7, 'assay': 18, 'value': 12, 'antirubella': 1, 'confirm': 68, 'detection': 17, 'severity': 34, 'varicella': 40, 'high': 15, 'frequent': 13, 'considerably': 3, 'limit': 8, 'pre-eclampsia': 1, 'steroid-treated': 1, 'uncontrolled': 1, 'Patients': 6, 'closely': 7, 'certain': 40, 'category': 21, 'deteriorate': 2, 'international': 8, 'quinine': 4, 'take': 15, 'seven': 8, 'endemic': 17, 'adequate': 16, 'majority': 11, 'combine': 12, 'clindamycin': 3, 'complete': 6, 'eradication': 2, 'parasite': 10, 'Alternatively': 1, 'children/': 1, 'atovaquoneeproguanil': 1, 'Quinine': 1, 'always': 4, 'accompany': 3, 'three': 41, 'orally': 2, 'total': 27, 'swallow': 3, 'publish': 18, 'intravenous': 9, 'artesunate': 2, 'Treatment': 11, 'hematologic': 8, 'artificial': 2, 'implant': 2, 'colitis': 2, 'prove': 12, 'suitable': 8, 'tularaemia': 1, 'Attendance': 1, 'blunt': 2, 'despite': 21, 'encourage': 21, 'monkeypox': 7, 'question': 15, 'bioterrorist': 1, 'article': 8, 'author': 9, 'threat': 22, 'novel': 24, 'mosquito-borne': 3, 'flavivirus': 4, 'Information': 6, 'fairly': 3, 'limited': 41, 'Based': 13, 'terms': 3, 'advise': 17, 'active': 17, 'insect': 4, 'repellant': 1, 'contain': 13, 'N-diethl-m-tolumide': 1, 'prior': 18, 'description': 4, 'Africa': 21, 'hospitalize': 35, 'eight': 7, 'comprehensive': 2, 'plan': 13, 'appropriately': 2, 'present': 70, 'gastrointestinal': 5, 'ingest': 1, 'contaminate': 8, 'American': 14, 'College': 4, 'Obstetricians': 5, 'Gynecologists': 2, 'environmental': 5, 'however': 38, 'decision': 13, 'risky': 1, 'enough': 5, 'merit': 1, 'official': 3, 'obstetrician-gynecologist': 1, 'provider': 19, 'first-line': 2, '60-day': 1, 'contraindication': 5, 'proscribe': 3, 'periodic': 1, 'perform': 27, 'similar': 43, 'would': 49, 'generally': 23, 'preferable': 1, 'Smallpox': 3, 'case-fatality': 8, 'sevenfold': 1, 'hemorrhagic': 10, 'smallpox': 20, 'Therefore': 22, 'intentional': 3, 'botulism': 1, 'consist': 8, 'supportive': 4, 'passive': 5, 'equine': 1, 'antitoxin': 1, 'tularemia': 1, 'prefer': 7, 'pestis': 1, 'gentamicin': 1, 'mention': 9, 'designate': 8, 'Working': 1, 'Group': 10, 'Civilian': 1, 'Biodefense': 1, 'feel': 1, 'appear': 18, 'outweigh': 13, 'severely': 8, 're-emerge': 1, 'understand': 8, 'vaccinia': 6, 'Lassa': 7, 'warrant': 14, 'reasonable': 5, 'Efforts': 1, 'toward': 6, 'achieve': 12, 'AIDS-free': 2, 'generation': 2, 'center': 10, 'around': 10, 'scale-up': 2, 'immediate': 2, 'life-long': 1, 'circumcision': 3, 'counseling': 4, 'focus': 19, 'concentrate': 1, 'tool': 5, 'combat': 6, 'insecticide-impregnated': 1, 'residual': 3, 'spraying': 1, 'insecticide': 2, 'artemisinin-based': 2, 'combination': 18, 'intermittent': 6, 'scaleup': 2, 'resistance': 9, 'vector': 10, 'accumulate': 1, 'assume': 4, 'fulminant': 28, 'fatality': 22, 'classical': 1, 'Mattison': 2, 'Nonetheless': 2, 'immunocompromized': 4, 'basement': 1, 'membrane-specific': 1, 'heparan': 1, 'sulfate': 1, 'proteoglycan': 1, 'protein': 26, 'perlecan': 1, 'agrin': 1, 'absent': 2, 'plasma': 20, 'administration': 18, 'Independently': 1, 'epidemic': 57, 'waterborne': 2, 'jaundice': 1, 'concomitant': 1, 'sporadic': 2, 'pattern': 7, 'enterically': 3, 'prescribe': 7, 'co-morbidities': 4, 'inclusion': 5, 'criterion': 11, 'regardless': 8, 'prematurely': 2, 'communicable': 4, 'interest': 11, "'chronic": 1, 'forget': 1, 'deficiency': 21, 'suffering': 8, 'tumour': 1, 'participate': 12, 'pilgrimage': 6, 'Besides': 2, 'successfully': 5, 'extend': 12, 'research': 47, 'pharmacokinetics': 4, 'drug-drug': 1, 'interaction': 6, 'especially': 90, 'wrong': 2, 'medicine': 23, 'indication': 5, 'right': 5, 'Broad-spectrum': 1, 'antibiotic': 27, 'narrow-spectrum': 1, 'suffi': 2, 'coprescribing': 1, 'absolutely': 2, 'base': 32, 'adjust': 5, 'weight': 14, 'organ': 6, 'product': 27, 'cancer': 11, 'confi': 2, 'rming': 1, 'presence': 26, 'Unnecessary': 1, 'highly': 17, 'price': 2, 'costly': 1, 'possibly': 9, 'equally': 3, 'ective': 4, 'originator': 1, 'brand': 2, 'generic': 2, 'lower-priced': 1, 'nonproprietary': 1, 'second-line': 2, 'third-line': 1, 'rst-line': 1, 'try': 1, 'questionable': 1, 'add': 7, 'better-characterised': 1, 'injectable': 1, 'analogue': 1, 'insulin': 1, 'therapeutic': 16, 'inappropriate': 2, 'outside': 4, 'sector': 2, 'agriculture': 1, 'elsewhere': 2, 'instance': 11, 'childbirth': 10, 'lifetime': 1, 'perception': 3, 'drinking': 4, 'Testa': 1, 'Reifman': 1, 'Shanchol': 1, 'Euvichol': 1, '2-dose': 1, 'schedule': 7, 'apart': 3, 'exception': 11, 'automatically': 2, 'close': 21, 'rubella': 21, 'Animal': 5, 'reproduction': 9, 'fail': 9, 'well-controlled': 6, 'wellcontrolled': 4, 'reaction': 16, 'investigational': 4, 'marketing': 4, 'Studies': 9, 'and/or': 15, 'involve': 28, 'clearly': 10, 'pair': 4, 'community-acquired': 4, 'October': 11, 'December': 8, 'distress': 8, 'routine': 17, 'pre-labor': 1, 'check-ups': 4, 'Changes': 4, 'physiology': 6, 'react': 3, 'differentially': 4, 'relative': 11, 'state': 27, 'emergence': 5, 'host': 6, 'investigate': 19, 'carefully': 5, 'falciparum': 5, 'influence': 8, 'parity': 6, 'consequence': 17, 'pronounce': 2, 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'evoke': 1, 'welfare': 1, 'ordering': 1, 'dengue': 16, 'barely': 1, 'certainty': 1, 'connect': 2, 'Mirambo': 1, 'Microbiology': 3, 'Immunology': 1, 'Weill': 1, 'Bugando': 1, 'School': 2, 'Catholic': 1, 'Allied': 1, 'Sciences': 1, 'Mwanza': 2, 'Tanzania': 3, 'seropositivity': 3, 'attending': 3, 'urban': 5, 'conflict': 3, 'whereas': 11, 'adjustment': 2, 'preclinical': 5, 'Administration': 3, 'partner': 22, 'teratogenicity': 6, 'neutralize': 4, 'titer': 5, 'expect': 12, 'warning': 1, 'cigarette': 2, 'package': 1, 'explicit': 2, 'pictograms': 1, 'vary': 3, 'timing': 3, 'Incidence': 1, 'seventies': 2, 'eighties': 1, 'reflect': 5, 'rising': 1, 'illicit': 1, 'elevation': 2, 'diaphragm': 1, 'functional': 5, 'Influenza': 20, 'almost': 8, 'underestimate': 1, 'cautious': 4, 'predict': 9, 'Criteria': 2, 'Thoracic': 4, 'Society/Infectious': 1, 'Diseases': 1, 'Society': 7, 'ATS/IDSA': 1, 'mechanical': 12, 'septic': 2, 'shock': 3, 'vasopressor': 2, 'minor': 2, 'tension': 1, 'hypoxemia': 1, 'Neuzil': 1, 'influenza-like': 8, 'April': 8, 'Mexico': 2, 'database': 4, 'subsequent': 8, 'Amantadine': 2, 'nasal': 5, 'Mechanical': 1, 'Immunoprophylaxis': 1, 'zoster': 7, 'globulin': 9, 'rigor': 5, 'malaise': 3, 'All-Hazards': 1, 'Preparedness': 1, 'Reauthorization': 2, 'diagnostics': 5, 'seroprevalence': 15, 'communication': 9, 'arbovirus': 3, 'implementation': 10, 'Aedes': 1, 'aegypti': 1, 'empower': 1, 'personal': 7, 'protection': 31, 'rodent': 10, 'own': 1, 'valacyclovir': 1, 'Fetal': 3, 'expansion': 2, 'abortifacient': 1, 'dosage': 6, 'Immunocompromised': 1, 'malnourish': 3, 'weak': 1, 'Whilst': 2, 'ideal': 2, 'explore': 8, 'coevolutionary': 1, 'dynamics': 1, 'host-parasite': 1, 'movement': 1, 'apparent': 2, 'strain': 17, 'immunocompetent': 6, 'feedback': 1, 'Benefits': 2, 'independently': 3, 'critically': 5, 'allergic': 11, 'intrauterine': 18, 'Germany': 4, 'advertise': 3, 'company': 4, 'distribute': 4, 'factory': 3, 'employee': 6, 'trachomatis': 1, 'first-void': 1, 'urine': 12, 'Rours': 1, 'embryotoxic': 1, 'Nevertheless': 6, 'Excluded': 1, 'toxicological': 1, 'Amelia': 1, 'phocomelia': 1, 'asplenia': 2, '800-670-6126': 2, '800-986-8999': 4, 'meningococcal': 6, '800-822-2463': 2, 'distinct': 4, 'practical': 5, 'pre-or': 2, 'recombinant': 9, 'impede': 2, 'litigation': 2, 'appearance': 3, 'litigious': 2, 'environment': 4, 'surround': 4, 'strengthen': 5, 'compel': 1, 'foster': 2, 'overcome': 6, 'obstacle': 2, 'aside': 2, 'market': 4, 'impediment': 2, 'birthday': 5, 'non-breastfeeding': 2, 'fifth': 2, 'Nutrition': 4, 'alleviate': 2, 'poverty': 4, 'trauma': 2, 'expenditure': 1, '1980s': 2, 'technology': 4, 'tradition': 1, 'school': 5, 'lunch': 3, 'nutrition': 4, 'Hospitals': 1, 'oblige': 1, 'citizenship': 1, 'western': 4, 'intramuscular': 3, 'wrongly': 1, 'viewing': 1, 'uncomplicated': 4, 'vivax': 2, 'benign': 4, 'simply': 2, 'age-matched': 4, 'anaemia': 17, 'form': 6, 'contraception': 2, 'thereafter': 2, 'exceptional': 2, 'etiological': 1, 'morbidly': 3, 'obese': 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'health-care': 5, 'coming': 4, 'bodily': 2, 'sometimes': 6, 'UNFPA': 1, '800,000': 3, '120,000': 1, 'lifesaving': 1, 'landmark': 2, 'mark': 8, 'perinatally': 1, 'exanthem': 3, 'nonimmune': 3, 'class': 7, 'White': 1, 'Numerous': 2, 'exanthematous': 3, 'section': 14, 'classified': 7, 'classify': 1, 'minimize': 3, 'Keighley': 1, 'screeningperhaps': 1, 'selective': 1, 'unusual': 6, 'immune-deficient': 1, 'Henderson': 1, 'President': 2, 'Obama': 2, 'announce': 1, 'ambitious': 3, 'evidence-based': 1, 'realise': 1, 'PEPFAR': 4, 'commit': 1, 'cumulatively': 3, 'voluntary': 4, 'precede': 4, 'cumulative': 2, 'PEPFAR-Haiti': 1, 'counselling': 5, 'lifelong': 3, 'HIVinfected': 4, 'domestic': 1, 'remain': 6, 'Assiri': 1, 'tonicclonic': 1, 'fall': 1, 'early-onset': 4, 'streptococcal': 3, 'steps': 1, 'identification': 4, 'reporting': 10, 'estimation': 2, 'share': 4, 'nation': 2, 'meaningful': 1, 'rough': 1, 'Assuming': 1, 'equal': 9, 'fourth': 1, '5-year': 2, 'age-specific': 1, 'fertility': 2, 'Using': 2, 'Anker': 3, 'supporting': 6, 'deserve': 3, 'Unusual': 1, 'frontline': 2, 'encounter': 2, 'immunodefi': 1, 'cient': 1, 'pose': 8, 'glycyrrhiza': 6, 'Obviously': 1, 'Korean': 4, 'correct': 3, 'ask': 8, 'herbal': 5, 'Donguibogam': 1, 'liquorice': 1, 'Antaeeum': 1, 'newspaper': 1, 'extract': 1, 'Symptoms': 3, 'flu-like': 4, 'meningoencephalitis': 2, 'meta-analysis': 2, 'probiotic': 1, 'doubleblind': 1, 'parallel': 7, 'placebo-controlled': 3, 'premenopausal': 2, '18-50': 1, 'acidification': 1, 'production': 7, 'glycogen': 1, 'utilization': 3, 'inhibition': 2, 'Several': 12, '52-54': 1, 'community': 27, 'caesarean': 4, 'spare': 1, 'Understandably': 1, 'choose': 2, 'private': 4, 'deter': 1, 'BioManguinhos': 2, 'comparative': 2, 'Vero-cells': 2, 'chimeric': 2, 'express': 10, 'Southeast': 4, 'Epigenetics': 1, 'transform': 1, 'palliative': 1, 'Methods': 9, 'clearance': 1, 'compartment': 1, 'semen': 6, 'breast': 8, 'smoker': 2, 'syndromic': 1, 'unspecified': 1, 'brief': 1, 'damage': 14, 'brainstem': 1, 'localization': 1, 'exponentially': 1, 'billion': 2, 'insufficient': 2, 'dietary': 4, 'energy': 1, 'calorie': 1, 'pre-school': 1, 'rigorous': 1, 'shortfall': 1, 'nutrient': 1, 'surely': 2, 'erythrocyte': 1, 'sickling': 1, 'erythrophagocytosis': 1, 'crisis': 2, 'Candidate': 1, 'subunit': 10, 'purify': 4, 'PFP-1': 1, 'immunogenic': 5, 'anti-PS': 1, 'formal': 1, 'demonstration': 3, 'actually': 1, 'pneumococcal': 3, 'Escherichia': 2, 'evident': 2, 'detectable': 4, 'antibody-specific': 2, 'characterize': 12, 'microflora': 1, '1/Gram': 1, 'stain': 1, 'smear': 2, 'score': 1, 'modify': 4, '2/identification': 1, 'culture': 19, 'anaerobic': 1, '3/species': 1, 'Atopobium': 1, 'Gardnerella': 1, 'vaginalis': 1, 'Sexually': 1, 'Athens': 1, 'Under': 1, 'cervicitis': 1, 'cytological': 1, 'examination': 5, 'muco-purulent': 1, 'discharge': 2, 'multicentre': 1, 'rectum': 1, 'Spain': 3, 'macrolides': 1, 'lincosamides': 1, 'make': 4, 'objective': 5, 'IP-10': 1, 'cross-sectional': 2, 'complement': 1, 'cytometry': 2, 'hemostasis': 1, 'angiogenesis': 1, 'regulation': 5, 'CXCL10/IP-10': 3, 'topic': 3, 'Cholestatic': 1, 'erythromycin': 3, 'estolate': 2, 'formulation': 4, 'Additionally': 7, 'Henry': 1, 'Koplik': 1, '-1927': 1, 'Nathan': 1, 'Strauss': 1, '-1931': 1, 'slum': 1, 'order': 22, 'summer': 1, 'Jerusalem': 2, 'Shaare': 1, 'Zedek': 1, 'nurse': 5, 'stations': 1, 'Tipat': 1, 'Halav': 1, 'Women': 6, 'Infants': 6, 'Children': 8, 'conceive': 1, 'persistence': 3, 'pregnancy-related': 2, 'feature': 12, 'prompt': 11, 'investigator': 9, 'immune-altering': 1, 'chicken': 1, 'gelatin': 1, 'mare': 1, 'misoprostol': 1, 'Moxidectin': 1, 'μg/kg': 1, 'along': 5, '1800s': 1, 'obstetrician': 4, 'Philipp': 1, 'Semmelweis': 1, 'disinfect': 1, 'hands': 1, 'puerperal': 1, 'childbed': 1, 'Louis': 1, 'Pasteur': 1, 'hemolytic': 5, 'Additional': 5, 'prisoner': 5, 'outline': 1, 'Subparts': 1, 'Human': 5, 'accurate': 4, 'tract': 9, 'Hsiung': 1, 'instead': 4, 'survey': 7, 'lesion': 4, 'high-titered': 1, 'low-titered': 1, 'visible': 1, 'lead': 3, 'evolve': 3, 'Unlike': 1, 'typical': 5, 'excise': 1, 'resolve': 3, 'September': 7, 'Secretary': 1, 'pursue': 1, 'importance': 14, 'injury': 4, 'reference': 2, 'Certainly': 1, 'cytokine': 9, 'tumor': 1, 'vaginosis': 4, 'vaginosis-associated': 1, 'reside': 2, 'uterus': 5, 'Andrews': 1, 'coworkers': 4, 'women2': 1, 'Gonorrhea': 1, 'trichomonas': 1, 'chlamydia': 2, 'Cytomegalovirus': 1, 'translate': 1, '40,000': 2, 'gonorrhea': 3, '80,000': 1, 'Trichomonas': 1, '200,000': 1, 'herpes': 3, 'simplex': 2, 'infected/colonized': 1, 'Unites': 1, 'excess': 3, 'Conversely': 2, 'transmitting': 7, '25,165': 1, 'Colombia': 2, 'safely': 8, 'attributable': 4, 'inulin': 3, 'osmotic': 2, 'diuresis': 2, 'adjuvanted': 8, 'closure': 1, 'containment': 2, 'respirator': 4, 'equipment': 1, 'Supplementary': 1, 'advisory': 2, 'offering': 1, 'conclusive': 1, 'things': 1, 'original': 2, 'non-adjuvant': 2, 'evidentiary': 1, 'Canadian': 3, 'Gynaecologists': 3, 'boards': 1, 'parent': 5, 'preferentially': 2, 'untimely': 1, 'ambiguous': 1, 'source': 5, 'Alberta': 1, 'credibility': 2, 'decision-makers': 1, 'jeopardize': 1, 'beyond': 4, 'priori': 2, 'cognitive': 3, 'dissonance': 1, 'department': 5, '2003-2004': 2, 'cluster': 3, 'interim': 6, 'hamster': 2, 'wastage': 4, 'hydrocephalus': 2, 'chorioretinitis': 2, 'yellow': 7, 'believe': 8, 'contracting': 5, 'Transplacental': 2, 'hypothesize': 4, 'survival': 2, 'advantage': 5, 'survive': 8, 'independent': 3, 'Multiple': 3, 'serosurveys': 2, 'symptom-based': 2, 'Borrelia': 2, 'Rarely': 3, 'Pregnant': 12, 'endocarditis': 4, 'bioterror': 2, 'biologic': 2, 'weapon': 3, 'diverse': 7, 'biliary': 2, 'atresia': 1, 'disproportionately': 8, 'Prenatal': 2, 'Serology': 1, 'pretransplant': 1, 'molecular': 6, 'quantitation': 1, 'gondii': 8, 'high-dose': 2, 'loading': 1, 'intravenously': 1, 'every': 6, 'hours': 16, 'marker': 3, 'oxidative': 2, '4-hydroxy-2-nonenal': 1, 'mmol/l': 1, 'Nation': 1, 'migrant': 2, 'hence': 2, 'expert': 3, 'sequela': 7, 'booster': 5, 'Chapter': 1, 'CMV-seropositive': 1, 'infective': 1, 'saliva': 1, 'disabled': 2, 'divide': 3, 'Diverting': 1, 'pediatric': 15, 'hospitalise': 5, 'Tyree': 1, 'broad': 4, 'ethnicity': 1, 'race': 1, 'pathogen-inactivated': 1, 'platelet': 4, 'workflow': 1, 'valid': 2, 'Coronavirus': 3, 'parts': 2, 'cite': 2, '-Many': 2, 'worry': 5, 'quarantine': 1, 'constraint': 2, 'moreover': 1, 'inter-urban': 1, 'transportation': 2, 'post-term': 1, 'Owing': 4, 'comorbidities': 14, 'voluntarily': 2, 'refrain': 1, 'Middle': 3, 'epicenter': 1, 'requirement': 4, 'GVIRF': 2, 'Plasmodium': 6, 'interrupt': 2, 'Mission': 1, 'Indradhanush': 1, 'launch': 4, 'Programs': 1, 'tetanus': 17, 'multiple': 9, 'service': 6, 'hesitancy': 1, 'comment': 9, 'operational': 1, 'efficiently': 2, 'precedent': 1, 'immunisation': 7, 'Novavax': 1, 'F-protein': 1, 'nanoparticle': 3, 'Phase': 6, 'palivizumab-competing': 2, 'neutralise': 1, 'elicit': 1, 'MedImmune': 1, 'Malarial': 1, 'dyspnoea': 2, 'conjunctival': 1, 'palmar': 1, 'pallor': 1, 'About': 2, 'one-fifth': 1, 'absorption': 1, 'intrinsic': 1, 'ileum': 1, 'postulate': 3, 'rationale': 1, 'Useful': 2, 'confirmatory': 1, 'thalassaemia': 2, 'sideroblastic': 2, 'poisoning': 4, 'falsely': 4, 'coexistent': 1, 'megaloblastic': 1, 'Anaemia': 1, 'occasionally': 5, 'microcytosis': 1, 'Serum': 3, 'ferritin': 1, 'Being': 1, 'acute-phase': 1, 'unreliable': 1, 'Levels': 1, 'hypothyroidism': 1, 'Erythrocyte': 1, 'protoporphyrin': 1, 'intermediate': 1, 'biosynthesis': 1, 'synthesis': 3, 'portable': 1, 'haematofluorometer': 1, 'Small': 1, 'field': 5, 'co-exist': 1, 'wash': 1, 'bilirubin': 2, 'fluorescent': 1, 'compound': 8, 'myeloid': 3, 'leukaemia': 1, 'slightly': 3, 'µmol/mol': 1, 'entering': 3, 'leaving': 4, 'folate': 2, 'wealthy': 1, 'soiltransmitted': 2, 'helminth': 1, 'store': 2, 'Vitamin': 2, 'though': 11, 'suboptimal': 3, 'Epidemiology': 1, 'Malaria-related': 1, '30-90': 1, '60-80': 1, 'low-income': 2, '50-80': 1, 'predominantly': 2, 'malaria-related': 2, 'pelvic': 1, 'gynaecological': 3, 'non-gynaecological': 1, 'Systemic': 2, 'cystic': 1, 'fibrosis': 2, 'foetus': 10, 'gadolinium': 1, 'discus': 5, 'hazard': 1, 'static': 1, 'time-varying': 1, 'magnetic': 1, 'fields': 3, 'heating': 1, 'pulse': 1, 'acoustic': 1, 'noise': 2, 'generate': 2, 'spatial': 1, 'encoding': 1, 'gradient': 1, 'Young': 5, 'middle-aged': 1, 'Lanzarini': 1, 'Pavia': 1, 'Milan': 1, 'Objective': 1, 'spiramycin': 4, 'titre': 3, 'seroconversion': 9, 'Toxoplasma': 5, 'twofold': 2, 'beginning': 5, 'pharmacologically': 1, 'Eighteen': 1, 'Fifteen': 3, 'interruption': 1, 'Results': 4, 'Maturation': 1, 'Toxoplasma-specific': 1, 'maturation': 1, 'reinforce': 4, 'Placental': 3, 'cytomegalovirus': 6, 'amongst': 3, 'preferably': 7, 'robust': 6, 'flaw': 2, 'Principally': 2, 'sharply': 3, 'Comparing': 2, '2000-08': 2, '2009-14': 2, 'demand': 9, 'modestly': 2, 'skilled': 5, 'attendant': 5, 'incrementally': 2, 'similarly': 7, 'modest': 2, 'exclusive': 2, 'rehydration': 3, 'care-seeking': 1, 'Increasing': 4, 'PMTCT': 15, 'acquiring': 4, 'figure': 2, 'averting': 2, '172·2': 2, 'costs': 3, '181·0': 2, 'baseline': 5, 'contraceptive': 2, 'fix': 3, 'transition': 2, 'Option': 6, 'replace': 4, 'linearly': 2, 'accordance': 6, 'UNAIDS': 4, 'social': 16, 'confound': 3, 'variable': 5, 'equip': 1, 'caring': 3, 'consciousness': 2, 'brain': 12, 'Earlier': 1, 'Brazilian': 4, 'recognition': 3, 'inflict': 2, 'Friday': 1, 'alert': 3, 'Level': 1, 'enhance': 10, 'precaution': 9, 'lymphocytosis': 2, 'anti-retroviral': 3, 'suffer': 10, 'Dutch': 1, 'Hunger': 1, 'Winter': 1, 'methylation': 1, 'marks': 1, 'gene': 3, 'differentiation': 1, 'TXNIP': 1, 'ABCG1': 1, 'PFKFB3': 1, 'METTL8': 1, 'sibling': 1, 'acyclovir': 3, 'prudent': 3, 'obstructive': 2, 'epidemiology': 5, 'Ordinance': 1, 'insert': 1, 'Creutzfeld-Jakob': 1, 'Febrile': 1, 'Icterohemorrhagic': 1, 'Syndrome': 4, 'post-vaccination': 1, 'typhus': 1, 'cholera': 2, 'disaster': 1, 'risk-group': 1, '-suffering': 1, 'Kühlmann': 1, 'Nigro': 2, 'CMVIG': 2, 'umbilical': 1, 'typically': 9, 'attend': 7, 'unit': 4, 'fulfill': 1, 'broaden': 5, 'L/min': 1, '≥92-95': 1, 'freely': 1, 'non-communicable': 2, 'native': 2, 'Indians': 1, 'Panel': 1, 'treatment-naïve': 1, 'selection': 4, 'conjunctivitis': 1, 'Seasonal': 4, 'internal': 2, 'Vulnerable': 1, 'definition': 2, 'Rennie': 1, 'General': 3, 'Medical': 6, 'Council': 2, '-that': 2, 'frail': 1, 'decision-making': 2, 'dementia': 1, 'psychiatric': 3, 'genetic': 4, '1Vulnerable': 1, 'capacity-that': 1, 'vitro': 8, 'anti-ZIKV': 9, 'annual': 12, 'Hajjis': 1, 'request': 3, 'optimum': 2, 'regular': 5, 'washing': 1, 'disposable': 1, 'adaptation': 6, 'communityacquired': 1, 'Generally': 6, 'Pneumocystis': 2, 'carinii': 2, 'AIDS-related': 3, 'Minnesota': 4, 'seek': 6, 'Before': 3, 'Transmission': 1, 'extrapulmonary': 1, 'radiograph': 2, 'abdominal': 3, 'shield': 2, 'Management': 4, 'invention': 1, 'Suspected': 1, 'Anti-D': 2, 'immunoglobulin': 7, 'ease': 1, 'careseeking': 1, 'HIVpositive': 1, 'abortus': 3, 'Vaginal': 1, 'sildenafil': 1, 'uterine': 1, 'artery': 1, 'estradiol': 2, 'thickness': 2, 'itraconazole': 2, 'Various': 5, 'eating': 2, 'typhoid': 2, 'immunosenescence': 2, 'alternatively': 1, 'utilize': 2, 'cellular': 2, 'likewise': 1, 'version': 1, 'effectively': 1, 'danger': 4, 'signal': 2, 'mucosal': 1, 'tailor': 2, 'toddler': 3, 'response^': 1, 'Risks': 2, 'likelihood': 5, 'TLR7/8': 1, 'agonist': 1, 'CL097': 1, 'restore': 3, 'secretion': 5, 'dapsone': 1, 'ratio': 11, 'intolerant': 1, 'inadequate': 3, 'exceed': 2, 'outweight': 1, 'woman-centred': 1, 'emphasis': 4, 'psychosocial': 1, 'Lavender': 1, 'Chinese': 8, 'responsibility': 1, 'towards': 5, 'cope': 1, 'first-time': 2, 'feelings': 4, 'exploratory': 1, 'descriptive': 1, 'correlation': 4, 'grave': 1, 'hold': 2, 'LifeGene': 1, 'web-based': 1, 'questionnaire': 4, 'biosamples': 1, 'Physical': 1, 'validate': 4, '20-35': 1, 'flulike': 1, 'carrier': 6, 'losses': 3, 'abort': 3, 'Accurate': 1, 'haemolytic': 1, '2019-nCoV': 10, 'claustrophobia': 2, 'contra-indicated': 2, 'factsheet': 1, 'update': 3, 'sufficient': 5, 'waiting': 2, 'list': 2, 'traveller': 14, 'prospect': 1, 'foreseeable': 1, 'H1N1/09': 4, 'Urgent': 1, 'promptly': 1, 'vertically': 1, 'Answers': 1, 'essential': 7, 'bally': 1, 'retrospectively': 3, 'analyse': 3, 'Zhongnan': 2, 'Wuhan': 9, 'trans': 1, 'mission': 1, 'RT-PCR': 7, 'qRT-PCR': 1, 'scan': 5, 'title': 2, 'laboratoryconfirmed': 3, 'lymphopenia': 1, 'Considering': 9, 'sequence': 2, 'similarity': 2, 'prognosis': 3, 'trend': 6, 'Future': 3, 'ascertain': 1, 'understanding': 6, 'responsible': 8, 'Workplace': 1, 'physically': 2, 'Measures': 1, 'low-and': 1, 'agricultural': 1, 'task': 1, 'outreach': 2, 'micronutrient': 1, 'breast-feeding': 2, 'purification': 1, 'pre-pregnant': 1, 'Epidemiological': 2, 'adhesins': 1, 'Afa/Dr': 1, 'cystitis': 1, 'definite': 2, 'volunteer': 1, 'Oseltamivir': 2, 'includ': 1, 'endorgan': 1, 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'influenzainduced': 1, 'H1N1pdm09': 11, 'aberrant': 1, 'hypothesise': 1, 'retroviral': 2, 'syncytin-1': 9, 'anti-viral': 1, 'non-vaccinated': 3, '2012-October': 1, 'Hunter': 1, 'advertisement': 1, 'characterisation': 1, 'venepuncture': 1, 'error': 1, 'replicate': 2, '14,787': 1, 'pg/mL': 6, '7311-22,264': 1, 'IFN-λ': 1, '756-2216': 1, 'stimulation': 1, '407-710': 1, 'pre-treated': 1, 'alone': 4, 'IL-1β': 1, 'Impaired': 1, 'Monocytes': 1, 'differentiate': 2, 'phenotypically': 1, 'mature': 1, 'HLA-DR': 1, 'stimulus': 1, 'monocyte-derived': 1, 'up-regulated': 1, 'IL-12p70': 1, 'skew': 1, 'capable': 1, 'Consistent': 1, 'innate': 3, 'CD303': 1, '/CD1c': 1, 'NK-and': 1, 'chemokine': 1, 'H1N1pdm2009': 1, 'NK-cell': 1, 'HN1N1pdm09': 1, 'entirely': 1, 'retrovirus': 1, 'manipulate': 1, 'swine-origin': 1, 'birthweight': 1, 'modern': 1, 'linkage': 1, 'reasonably': 1, 'antiinfluenza': 1, 'inconclusive': 2, 'efficiency': 1, 'binding': 2, 'entry': 2, 'Spanish': 1, 'Peripheral': 1, 'mononuclear': 1, 'co-cultured': 1, 'HRV43': 1, 'HRV1B': 1, 'IFN-γ': 3, 'well-documented': 1, 'dysregulated': 1, 'deprivation': 1, 'post-mortem': 1, 'non-fatal': 1, 'geometric': 1, 'A/California': 1, 'A/Perth': 1, 'plasmablast': 1, 'Shenyang': 1, 'imbalanced': 1, 'anti-H1N1': 1, 'subtypes': 1, 'doubles': 1, 'connection': 1, 'endocrinology': 1, 'excite': 1, 'coordination': 1, 'sampling': 1, 'influenzainfected': 1, '-vaccinated': 1, 'validation': 2, 'Tippoo': 2, 'Biovac': 2, '10-40': 2, 'pentavalent': 2, 'conjugate': 4, 'capsular': 2, 'Globally': 1, '2009-2010': 1, 'importantly': 2, 'Mongolia': 1, '2013-2014': 1, 'Irish': 1, 'cultural': 1, 'prohibition': 1, 'habit': 1, 'Empirical': 1, 'reestablish': 1, 'High-dose': 1, 'overestimation': 1, 'pre-SARS': 1, 'Pre-F': 1, 'Taleb': 1, 'face-masks': 1, 'usual': 1, 'Carles': 1, 'risk-groups': 1, 'unequivocal': 1, 'utmost': 2, 'METHODS': 1, 'Log-linear': 1, 'regression': 1, 'Wilcoxon-rank': 1, 'Prevalence': 1, 'non-HRV': 1, 'remainder': 1, '3-year': 1, 'weekly': 2, '16-fold': 1, 'Limited': 1, 'HRV-associated': 1, 'midwife': 2, 'Action': 2, 'channel': 2, 'medically': 2, 'socially': 2, 'township': 2, 'village': 2, 'Socioeconomic': 2, 'inequality': 2, 'detract': 2, 'achievement': 2, 'near-universal': 2, 'influenza-positive': 1, 'congenitally': 1, 'remarkably': 1, 'ready-to-eat': 1, 'replication-competent': 1, 'stakeholder': 1, '2016c': 1, 'Thereby': 1, 'new-borns': 2, 'Pierson': 2, 'Graham': 2, 'immediately': 2, 'HBeAg': 4, 'mother-to-infant': 1, '1990s': 1, 'Taiwanese': 2, 'foreign': 2, 'immigration': 1, '10-year': 1, 'HBeAg-positive': 1, 'spouse': 1, 'isotypes': 1, 'decent': 1, '17-67': 1, 'Seventy': 1, 'correctly': 1, 'publicise': 1, 'flu-related': 1, 'low-risk': 1, 'maker': 2, 'HEVinfected': 1, 'to~30': 1, 'nursing-mothers': 1, 'smartphone': 1, 'instrument': 1, 'reflection': 1, 'spectroscopy': 1, 'phenylketonuria': 1, 'inherent': 1, 'sub-populations': 1, 'pneumothoraces': 1, 'expat': 1, 'unreachable': 1, 'falciparum-exposed': 1, 'sympatric': 1, 'non-exposed': 1, 'VSAPAM': 1, 'non-PAM': 1, '-such': 1, 'Ofori': 1, 'obscure': 1, 'inconsequential': 1, 'remote': 1, 'accessible': 1, 'Hennigan': 1, 'Zikaaffected': 1, 'Lima-Camara': 1, 'differential': 1, 'Knowledge': 1, 'Viruses': 1, 'REVIEW': 1, 'Family': 1, 'icddr': 2, 'CHRWs': 1, 'sub-center': 1, 'already-approved': 1, 'ready-to-use': 1, 'library': 1, 'FDA-approved': 3, 'Ery-Est': 5, 'efficiently75-2': 1, 'g/day': 2, 'ureaplasma': 1, 'gravida': 1, 'powerful': 1, 'repurposed': 1, 'respondent': 1, 'non-vaccination': 1, '19-64': 1, '15,000': 1, 'diaphragmatic': 2, 'splint': 2, 'transcutaneous': 2, 'carbon': 1, 'dioxide': 1, '1-hour': 1, 'Eight': 1, 'Twenty-eight': 1, '20119': 1, 'N95-masks': 1, '20-minute': 1, 'hyperventilation': 1, 'enlarge': 1, 'exercising': 1, 'N95-mask': 2, 'deficit': 1, 'correspond': 2, 'mid-pregnancy': 1, 'minute': 1, 'break': 1, 'albeit': 1, 'optimism/pessimism': 2, 'Ghanaian': 2, 'cross-cultural': 1, 'optimism/pes-simism': 1, 'health-related': 2, 'three-sample': 1, 'Ghana': 2, 'optimism': 2, 'pessimism': 2, 'self-assessed': 1, 'self-perceived': 1, 'selfassessed': 1, 'Health-Related': 1, 'Quality': 1, 'HRQOL': 1, '3000-3500': 2, '500-600': 1, '-12,000': 1, 'three-country': 1, 'LOT-R': 2, 'leaders': 1, 'youth': 1, 'adoption': 2, 'authorisation': 1, 'Kaloba®': 1, 'SARI4': 1, 'SINAN': 3, 'thrombophilia': 1, 'comorbidity': 1, 'mother-': 1, 'HIV-exposed': 1, 'HIV-consumers': 1, 'discovery': 1, 'synthetic': 1, 'cannabinoids': 1, 'cathinones': 1, 'Neonatal': 1, 'intra-partum': 1, 'intra-rectal': 1, 'Romania': 1, 'letter': 1, 'crowd': 1, 'Remarkably': 1, 'HEV-related': 1, 'TGF-β1': 1, 'Rothberg': 1, 'putative': 2, 'in-house': 1, 'ZIKV-endemic': 2, 'Laboratories': 1, 'exceptionally': 1, 'downregulation': 1, 'downstream': 2, 'MYD88': 2, 'FHF-E': 2, 'causal': 1, 'opt': 1, 'accessibility': 1, 'transcriptome': 1, 'IgManti-HEV': 1, 'transcript': 3, 'NK/NKT': 1, 'immunomodulation': 1, 'well-defined': 1, 'Sehgal': 1, 'regulate': 2, 'diseaseWe': 1, 'self-recovering': 2, 'IgG-anti-HEV': 1, 'upregulated': 2, 'non-specific': 1, 'two-dimensional': 1, 'hierarchical': 1, 'clustering': 1, 'immune-related': 1, 'diseaseincluding': 1, 'confounders': 1, 'discount': 1, 'residence': 1, 'cavity': 1, 'H1N1pdm': 1, 'reliable': 2, 'Norway': 1, 'schoolteacher': 1, 'Parvovirus': 1, 'erythrovirus': 1, 'speaking': 1, 'biochemical': 1, 'nonasthmatic': 3, 'two-thirds': 1, 'tightness': 1, 'Whole-course': 1, 'fluctuation': 1, 'longacting': 1, 'beta2-agonists': 1, 'μg/day1': 1, 'glucocorticoids-taking': 1, 'μg/ml': 1, 'theophylline': 3, 'multicenter': 1, 'withdrawal': 2, 'glucocorticoid': 2, 'EXPECT': 1, 'omalizumab': 3, 'cut-off': 1, 'monoclonal': 2, 'mepolizumab': 1, 'reslizumab': 1, 'benralizumab': 1, 'partially': 1, 'allergen': 1, 'hyperreactivity': 1, 'continuously': 1, 'inhale': 2, 'bronchodilator': 1, 'adrenal': 2, 'hydrocortisone': 1, 'incorrect': 1, 'Viral': 1, 'find': 1, '30-50': 1, 'CHIKV': 2, 'envisage': 1, 'manufacture': 1, '13-64': 1, 'specialty': 1, 'ward': 1, 'Kenya': 3, 'phenacetin': 1, 'sulfadiazine': 1, 'Meta-analysis': 1, 'Paulo': 5, 'notify': 3, 'Adolfo': 1, 'socio-demographic': 1, 'hematocrit': 1, 'creatine': 1, 'phosphokinase-CPK': 1, 'dehydrogenase-LDH': 1, 'glutamic': 1, 'oxaloacetic': 1, 'transaminase-GOT': 1, 'creatinine': 1, 'random': 1, 'proper': 3, 'noteworthy': 1, 'goal': 1, 'nonimmune/': 1, 'Returning': 1, 'population-wide': 1, 'quantity': 1, 'encounter-those': 1, 'light': 1, 'proteomic': 1, 'intraamniotic': 1, 'existence': 1, 'IL1RL1': 1, 'Previously': 1, '11-kDa': 1, 'proteolytic': 1, 'fragment': 1, 'insulin-like': 1, 'IGFBP1': 1, 'Georgia': 1, 'smaller': 1, 'Torjesen': 1, 'persistent': 1, 'discretion': 1, 'Guatemala': 2, 'amplify': 1, 'clarify': 1, 'Guillain-Barre': 1, 'ivermectin': 1, 'alternate': 1, 'topical': 1, 'Topical': 1, 'sulfur': 1, 'adaptive': 1, 'capability': 1, 'neuropathology': 1, 'biomedical': 1, 'translational': 1, 'neurologist': 1, 'obstetrician/': 1, 'gynecologist': 1, 'Predisposing': 1, 'hematopoietic': 1, 'chemotherapy': 1, 'sufferer': 1, 'metagenomics': 1, 'commuting': 1, 'Huzly': 1, '33,41,42': 1, 'kindergarten': 1, 'survivor': 2, 'congruent': 1, 'Toxoplasmosis': 1, 'genotype-1-infected': 1, 'Asogun': 1, 'namely': 1, 'contemplate': 1, 'autophagy': 1, 'anti-malaria': 1, 'microvascular': 1, 'endothelial': 1, 'hBMECs': 1, 'raising': 1, 'endosomal': 2, 'azathioprine': 1, 'purine': 1, 'nonetheless': 1, 'remark': 1, 'Egyptian': 1, 'locality': 1, 'R103451': 1, 'EDIII-based': 1, 'E298-409': 1, 'entity': 1, 'Seeking': 1, 'outcomes21': 1, 'messaging': 2, 'behaviors-seeking': 1, 'care-are': 1, 'Lessler': 1, 'upset': 1, 'branch': 1, 'venue': 1, 'pharmacy': 1, 'methadone': 1, 'heroin': 1, 'injection-related': 1, 'pessimistic': 1, 'Peking': 1, 'formally': 1, 'thinking-the': 1, 'predominant': 1, 'women-versus': 1, 'mindsetaltering': 1, 'cell-inducing': 1, 'exogenous': 1, 'self-adjuvanting': 1, 'constrain': 1, 'televise': 1, 'publicity': 1, 'slaughter': 1, 'industry': 1, 'serum-neutralizing': 1, 'maternally-acquired': 1, 'Native': 1, 'Americans': 1, 'Alaska': 1, 'prone': 1, 'declare': 1, 'Concern': 1, 'telephone': 1, 'waiver': 1, 'Files': 1, 'non-randomized': 1, 'oversight': 1, 'board': 1, 'Trial': 1, 'aboriginal': 1, 'aforementioned': 1, 'Abnormal': 1, 'disappearance': 1, 'lactobacillus': 1, 'pathologic': 1, 'fertile': 1, 'invert': 1, 'Strategies': 1, 'venereal': 1, 'Candid': 1, 'partial': 1, 'cross-protection': 1, 'arenavirus': 1}
word_counter = collections.Counter(wordcount)
for word, count in word_counter.most_common(2):
    print(word, ": ", count)woman :  3601
pregnant :  3389
total_count = len([x for x in word_counter.values() if x > 150]) # take words where occurence more than 50
lst = word_counter.most_common(total_count)
df = pd.DataFrame(lst, columns = ['Word', 'Count'])
display(df)<class 'list'>
df.plot.bar(x='Word',y='Count')
plt.show()_____no_output_____def tag_documents(wordcount, sentences):
    tagged_docs = []
    word_counter = collections.Counter(wordcount)
    tag = ' '.join([x[0] for x in word_counter.most_common(2)])
    complete_text_for_topics = ""
    for ix in range(len(sentences['title'])):
        full_text = ''.join(x for x in sentences['sents'][ix])
        complete_text_for_topics += full_text + "\n\n"
    tagged_docs.append((tag, complete_text_for_topics))
    return tagged_docs

tagged_docs = tag_documents(wordcount, relevant_sentences)
df_tags = pd.DataFrame(tagged_docs, columns = ['Tag', 'Full_Text'])
display(df_tags)_____no_output_____display(df_covid)_____no_output_____def compute_word_count(sentences):
    wordcount = {}
    tokens = prepare_text_for_lda(sentences)
    for word in tokens:
        if word not in wordcount:
            wordcount[word] = 1
        else:
            wordcount[word] += 1
    return wordcount

def compute_tag_documents(wordcount):
    word_counter = collections.Counter(wordcount)
    tag = ' '.join([x[0] for x in word_counter.most_common(2)])
    return tag

def generate_tags_for_each_text():
    text_content = df_covid.text.values
    title = df_covid.title.values
    lst_of_tags_per_doc = []
    for sent in tqdm.tqdm(range(len(text_content))):
        wordcount_entire = compute_word_count(text_content[sent])
        tag_for_sent = compute_tag_documents(wordcount_entire)
        lst_of_tags_per_doc.append((tag_for_sent, text_content[sent]))
    return lst_of_tags_per_doc

lst_of_tags_entire = generate_tags_for_each_text()
df_tags_entire_set = pd.DataFrame(lst_of_tags_entire, columns = ['Tag', 'Full_Text'])
display(df_tags_entire_set)100%|██████████| 33375/33375 [52:22<00:00, 10.62it/s]
# save the df
df_tags_entire_set.to_csv('tagged_texts.csv', index=False, header=True)_____no_output_____
</code>

gene expression
microbiome
RNA
genomics
biomarkers
immunology
biology
ecology
virology
metagenomics
evolution
epidemiology