1. Introduction

2. Observations and Source Properties  
2.1. Herschel/Hi-GAL  
2.2. CO(1-0)  
2.3. Distance Determination  
2.4. Compact Source Properties  
2.5. Candidate Protostellar Clump Selection Criteria  
2.6. Mass Estimate of Molecular Clouds

3. Clustered Evolution of Massive Clumps and SFR Estimate  
3.1. Star-Formation Rate  
3.2. SFR from FIR Estimator  
3.3. Conversion Efficiency  
3.4. Clump Formation Efficiency  
3.5. Effect of Distance Errors on SFR Values  
3.6. Completeness

4. SFR at the Tips of the Bar  
4.1. Star Forming Regions in the 4th Quadrant

5. Conclusions