1. Introduction  
2. Observations, data reduction and sample selection  
2.1. Observational data and target selection  
2.2. Spectral feature selection  
3. Measuring temporal variations  
3.1. The effect of spectral resolution  
3.2. Other artifacts  
3.3. Searching for temporal variations in the DIBs  
3.4. Searching for temporal variations in interstellar atomic and molecular lines  
4. Results  
4.1. The diffuse interstellar bands  
4.2. Molecular and Atomic lines  
5. Discussion  
5.1. Variations in HD 167264  
5.2. Variations in HD 147933  
5.3. Variations in the λλ 4727 and 5780 DIBs  
6. Summary and conclusions